Email
Print
Superdisintegrants Market Overview
The Superdisintegrants Market size is estimated to reach $571.7 million by 2027, growing at a CAGR of 7.7% during the forecast period 2022-2027. Superdisintegrants are applied as a structural weakener for the disintegrable solid dosage forms. Superdisintegrants are the class of disintegrants that have been demonstrated to be efficient at excipient concentrations as reduced as 2% to 10% in comparison with conventional disintegrant starches, which may require concentrations as great as 20% (Augsburger et al. 2007). Presently, the principal superdisintegrants utilized are sodium starch glycolate, croscarmellose sodium, crospovidone and polacrilin potassium. The increasing application of superdisintegrants in the production of disintegrating oral formulations is set to drive the Superdisintegrants Market. The snowballing application of superdisintegrants as viscosity-enhancing agents in drug-loaded films is set to propel the growth of the Superdisintegrants Industry during the forecast period 2022-2027. This represents the Superdisintegrants Industry Outlook.
Superdisintegrants Market Report Coverage
The “Superdisintegrants Market Report
- Forecast (2022-2027)” by IndustryARC, covers an in-depth analysis of the
following segments in the Superdisintegrants
Market.
by Product Type: Natural Superdisintegrants and Synthetic Superdisintegrants.
by Formulation: Tablets & Capsules and Mouth Dissolving Films.
by Geography: North America (the US, Canada and Mexico), Europe (Germany, France, the UK,
Italy, Spain, Russia and the Rest of Europe), Asia-Pacific (China, Japan, South
Korea, India, Australia & New Zealand and the Rest of Asia-Pacific), South
America (Brazil, Argentina, Chile, Colombia and the Rest of South America) and the Rest Of
The World (the Middle East and Africa).
Key Takeaways
- Geographically, North America (Superdisintegrants market share) accounted for the highest revenue share in 2021 and it is poised to dominate the market over the period 2022-2027 owing to the great industrialization fueling the production of pharmaceuticals in the region.
- The Superdisintegrants Market growth is being driven by the surging inclusion of Superdisintegrants in solid dosage forms like capsules or tablets. However, the concern associated with safety and quality is one of the major factors hampering the growth of the Superdisintegrants Market.
- The Superdisintegrants Market Detailed Analysis on the Strengths, Weaknesses and Opportunities of the prominent players operating in the market would be provided in the Superdisintegrants Market report.
Superdisintegrants Market: Market Share (%) by Region, 2021
For More Details on This Report - Request for Sample
Superdisintegrants Market Segment Analysis - by Product Type
The Superdisintegrants Market based on product type can be further segmented into Natural Superdisintegrants and Synthetic Superdisintegrants. The Synthetic Superdisintegrants Segment held the largest share of the Superdisintegrants market in 2021. This growth is fueled by the surging application of crospovidone with the capability to stabilize the amorphous state of medications attributed to inhibition of drug recrystallization and a very quick solidification rate. The wonderful disintegration and dissolution-enhancing impact, typically applied in the preparation of tablets, granules and capsules are further propelling the growth of the Synthetic Superdisintegrants segment.
Furthermore, the Natural Superdisintegrants segment is estimated to grow with the fastest CAGR of 8.3% during the forecast period 2022-2027 owing to the soaring benefits of natural superdisintegrants like ispaghulla, gellan gum, fenugreek seed mucilage and gum karaya over Synthetic Superdisintegrants, like biodegradability, chemical inertness and non-toxicity.
Superdisintegrants
Market Segment Analysis - by Formulation
The Superdisintegrants Market
based on formulation can be further segmented into Tablets &
Capsules and Mouth Dissolving Films. The Tablets & Capsules Segment held the largest share of the Superdisintegrants market in 2021. This growth is owing to the surging benefits
of tablets like lengthier shelf life, precise dosing and cost-effectiveness. Tablets
and capsules have fast-dissolving dosage forms. The superdisintegrants like
sodium starch glycolate as excipients included in instant discharge and oral
dispersible tablet formulations at low concentrations are further propelling
the growth of this segment.
Furthermore, the Mouth
Dissolving Films segment is estimated to grow with
the fastest CAGR of 8.5% during the forecast
period 2022-2027 owing to the soaring benefits, rare characteristics, accessibility
of bigger surface area for very quick disintegration and dissolution in the
oral cavity, precise dosing and very quick onset of action.
Superdisintegrants Market Segment Analysis - by Geography
The Superdisintegrants Market based on geography can be further segmented into North America, Europe, Asia-Pacific, South America and the Rest of the World. North America (Superdisintegrants Market) held the largest share of the Superdisintegrants market with 37% of the overall market in 2021. The growth of this region is owing to the presence of key players like Ashland Global Holdings Inc., in the North American region. The well-entrenched healthcare infrastructure is further propelling the growth of the Superdisintegrants Industry, thereby contributing to the Superdisintegrants Industry Outlook, in the North American region.
Furthermore, the Asia-Pacific region is estimated to be the region with the fastest CAGR over the forecast period 2022-2027. This growth is driven by the factors like the surging application of orally disintegrating tablets in the Asia-Pacific region. The growing R&D activities are further fuelling the progress of the Superdisintegrants Market in the Asia-Pacific region.
Superdisintegrants Market Drivers
Synthesis of Novel Superdisintegrants for Pharmaceutical Tableting Based on Functionalized Nanocellulose Hydrogels:
Superdisintegrants are typically utilized at a low level in the solid dosage form, usually 1-10 % by weight relative to the total weight of the dosage unit. In certain research, nanocrystalline cellulose (NCC) was removed from microcrystalline cellulose (MCC) through the sulfuric acid hydrolysis process. NCC derivatives have been synthesized by Itaconic acid/Hydroxyethyl methacrylate (IA/HEMA) through maleic anhydride (MA) to gain rare swellability characteristics to accomplish superabsorbent cellulose-based nano hydrogel with the cross-linking system. The disintegration performance of prepared tablets was compared with tablets constituted of sodium starch glycolate (SSG) and MCC as positive and negative controls. The outcomes demonstrate that the disintegration time of tablets formulated with synthesized modified NCC (m-NCC) reduced dramatically compared to additional disintegrants. The dissolution analysis demonstrated appropriate conditions for total drug release in a shorter time. The synthesis of novel Superdisintegrants for pharmaceutical tableting based on functionalized nanocellulose hydrogels is therefore fuelling the growth of the Superdisintegrants Market during the forecast period 2022-2027.
Present Strategic Developments in the Application of Superdisintegrants for Drug Delivery:
The suggested concentration of cross-linked sodium carboxymethylcellulose is 0.5–2.0%, which can be utilized up to 5.0% L-HPC (Low substituted Hydroxy propyl cellulose). Presently, superdisintegrants have been proposed for drug delivery systems as alternative approaches to augment the effectiveness of therapy. Though superdisintegrants are well recognized and utilized in solid dosage forms, investigations on strategies for the development of drug delivery systems applying superdisintegrants are insufficient. The present investigation examines the application of superdisintegrants in regulated drug release dosage formulations. This overview of superdisintegrants covers established strategies, types (inclusive of synthetic and natural materials), dosage forms and methods and would assist to enhance drug delivery systems. The present strategic developments in the application of superdisintegrants for drug delivery are therefore driving the growth of the Superdisintegrants Industry, thereby contributing to the Superdisintegrants Industry Outlook during the forecast period 2022-2027.
Superdisintegrants Market Challenges
The High-priced, Time-consuming and Fragile Nature of Superdisintegrants:
The percentage range of crospovidone, croscarmellose sodium and sodium starch glycolate utilized is 1-3%, 2-5% and 4-6%, respectively. Superdisintegrants are more sensitive and hygroscopic in quality. Freeze drying is the procedure in which water is sublimed from the product consequent to it being frozen. This method builds an amorphous porous structure that can dissolve very quickly. However, the principal limitation of this method is that it is high-priced, time-consuming and fragile, which makes traditional packaging inappropriate for these products. These issues are thus hampering the growth of the Superdisintegrants Market.
Superdisintegrants Industry Outlook
Novel product launches, mergers and acquisitions, regional expansions and R&D activities are key strategies adopted by players in the Superdisintegrants Market. The top 10 companies in the Superdisintegrants market are:
- BASF SE
- Ashland Global Holdings Inc.
- DuPont de Nemours, Inc.
- Roquette Freres
- DFE Pharma
- JRS Pharma
- Asahi Kasei Corporation
- Merck KGaA
- Corel Pharma Chem
- FMC Corporation
Recent Developments
- In February 2022, BASF’s Care Creations® increased the standard for the smart development of sustainable, high-performing personal care products. This was performed by the launch of Emollient Maestro. AI-empowered simulation allows quicker, more targeted prototyping and effective product development.
- In May 2020, BASF introduced a novel fungicide solution based on Revysol® in China. Melyra® fungicide powered by Revysol® conveys powerful performance against ailments. It fits the topmost level of regulatory standards.
- In April 2020, BASF introduced an e-commerce portal with Agilis for its OPPANOL product family. U.S. customers can place orders, track the status and produce safe payments online. The e-commerce distribution portal is planned to acquire effectiveness and transparency.
Relevant Reports:
Report Code: FBR 0041
Report Code: CMR 0283
Report Code: FBR 0086