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Human Liver Models Market Overview
Human Liver Models Market size is $163.40M in 2019, growing at a CAGR of 11.4% during the forecast period 2020-2025. A human liver model is a structure that is used to check toxicity associated with the drug which may result in liver failure or other related liver disease. This helps to create a better understanding of liver disease and complex spatial relationship of internal anatomy of liver. It enables to develop a better understanding of liver disease and complex spatial relationships of the internal anatomy of the liver. The advanced liver models are mini-organs or organoids that are expected to replicate human liver physiology, anatomy, and functions from molecular layer upward. Liver organoids have numerous applications owing to their advantages over cell cultures such as their ability to mimic the tissue function and disease pathology. They are thus used in research applications, disease modelling, drug screening, gene therapy and organ replacement.
Report Coverage
The report: “Human Liver Models Market – Forecast (2020-2025)”, by IndustryARC covers an in-depth analysis of the following segments of the Human Liver Models Market.
By Drug Discovery Platforms: Liver Organoids, Liver-On-A-Chip, 2D Model, Animal Model and 3D Bioprinting.
By Application: Education, Drug Discovery and Others.
By Geography: North America, Europe, Asia-Pacific and Rest of the World.
Key Takeaways
- Increasing demand for operative treatment methods regarding the liver is set to propel the growth of the market.
- Increasing number of initiatives to create an awareness regarding the liver organoids is the driving factors for the growth of Human Liver Models market.
- Increasing R&D funding and venture capital investments for the development of liver models aiding growth towards the market.
- Europe region is estimated to record the fastest growth rate during the forecast period 2020-2025.
By Application - Segment Analysis
In 2019, Drug Discovery segment dominated the Human Liver Models Market in terms of revenue is estimated to grow at a CAGR of 12.0% owing towards the low risk by early detection of hepatic toxicity. Animal models and 2D models are being used traditionally and have various limitations. Thus they are being replaced by 3D bio printed models or chip models. The adoption of in vitro models for drug discovery is rising owing to the disadvantages of animal models such as they do not mimic human functions and humanized animals are more expensive. Drug discovery by pharmaceutical companies require culture of human liver cells for toxicology studies. Liver models have characteristic functions that are used in preclinical metabolism and safety studies of candidate drugs abetting towards the market’s growth.
Geography - Segment Analysis
In 2019, the North America region dominated Human Liver Models Market in terms of revenue is estimated to grow at a CAGR of 10.4% owing towards the presence of established in this region. This growth can be attributed towards the increasing research & development initiatives and government support for the improvement of the healthcare sector. The increasing awareness about the health and availability of new treatment methods drives the market in this region is key factors in the growth of the Human Liver Models market. Europe is estimated to record the fastest growth rate during the forecast period 2020-2025.
Drivers – Human Liver Models Market
- Increasing Need For Early Detection Of Drug Toxicity In Patients
The increasing need for the early detection of drug toxicity to minimize financial losses owing to late-stage drug failure is the growing factor for Human Liver Models Market. Liver models are required to study the common problems at a late stage of the drug development process, where failure is at its most expensive, and how the trend of growing attrition rates is slowed in the future is also contributing to the market growth.
Challenges – Human Liver Models Market
- Lack of Expert Professionals
High skills are required with the development and total process of making effective liver models. There has been a shortage of people able to excel in these positions in the community, making an extremely negative high-impact on the work process hampering the market’s growth. Lack of integration of patient’s priorities into the care plan can result in undue focus on curative care even with dwindling chances of transplant, rather than proactively addressing supportive and palliative care goals are main factors restraining the market’s growth.
Human Liver Models Industry Outlook
Product Launches was the key strategy of the players in the Human Liver Models Industry. Human Liver Models top 10 companies include CN Bio Innovations, Corning Incorporated, Emulate, Inc., Hurel Corporation, InSphero, BioIVT, Regenovo, CellLink Lifescience, Pandorum, Organovo Holdings Inc. and Organovo Holdings Inc.
Acquisitions/Product Launches
- In March 2017, Hurel Corporation acquired entered into an agreement with Johnson & Johnson Pharmaceutical Research and Development to develop microfluidic technology with a view to launch the world’s first in vitro test of first-pass liver bioavailability in humans.
- In July 2020, InSphero launched Online Store to Streamline Ordering Process for Researchers Heading Back the Bench as COVID-19 Shutdown Ends. Online purchasing options for assay-ready 3D insight human liver microtissues is to help eliminate 3D model developments delays for labs ready to resume compound testing and risk assessment.
1. Human Liver Models Market Overview
1.1 Definitions and Scope
2. Human Liver Models Market - Executive Summary
2.1 Market Revenue and Key Trends
2.2 Key trends by Drug Discovery Platforms
2.3 Key trends by Application
2.4 Key trends by Geography
3. Human Liver Models Market – Comparative Analysis
3.1 Product Benchmarking
3.2 Financial Analysis
3.3 Patent Analysis
3.4 Pricing Analysis
4. Human Liver Models Market - Startup Companies Scenario (Premium)
4.1 Key Startup Company Analysis by
4.1.1 Investment
4.1.2 Revenue
4.1.3 Venture Capital and Funding Scenario
5. Human Liver Models Market – Industry Market Entry Scenario Premium (Premium)
5.1 Regulatory Framework Overview
5.2 New Business And Ease Of Doing Business Index
5.3 Case Studies of Successful Ventures
6. Human Liver Models Market Forces
6.1 Market Drivers
6.2 Market Constraints/Challenges
6.3 Porters Five Force Model
6.3.1 Bargaining power of suppliers
6.3.2 Bargaining powers of customers
6.3.3 Threat of new entrants
6.3.4 Rivalry among existing players
6.3.5 Threat of substitutes
7. Human Liver Models Market – Strategic Analysis
7.1 Value Chain Analysis
7.2 Opportunities Analysis
7.3 Market Life Cycle
8. Human Liver Models Market – By Drug Discovery Platforms (Market Size –$Million/$Billion)
8.1 Liver Organoids
8.2 Liver-On-A-Chip
8.3 2D Model
8.4 Animal Model
8.5 3D Bioprinting
9. Human Liver Models Market – By Application (Market Size –$Million/$Billion)
9.1 Education
9.2 Drug Discovery
9.3 Others
10. Human Liver Models Market - By Geography (Market Size –$Million/$Billion)
10.1 North America
10.1.1 U.S.
10.1.2 Canada
10.1.3 Mexico
10.2 Europe
10.2.1 U.K.
10.2.2 Germany
10.2.3 France
10.2.4 Italy
10.2.5 Spain
10.2.6 Rest of Europe
10.3 Asia-Pacific
10.3.1 China
10.3.2 Japan
10.3.3 India
10.3.4 South Korea
10.3.5 Australia
10.3.6 Rest of Asia-Pacific
10.4 Rest of the World
10.4.1 South America
10.4.2 Middle East
10.4.3 Africa
11. Human Liver Models Market - Entropy
12. Human Liver Models Market – Industry/Segment Competition Landscape (Premium)
12.1 Market Share Analysis
12.1.1 Global Market Share – Key Company
12.1.2 Market Share by Region – Key Company
12.1.3 Market Share by Countries – Key Company
13. Human Liver Models Market – Key Company List by Country Premium (Premium)
14. Human Liver Models Market Company Analysis
14.1 Company 1
14.2 Company 2
14.3 Company 3
14.4 Company 4
14.5 Company 5
14.6 Company 6
14.7 Company 7
14.8 Company 8
14.9 Company 9
14.10 Company 10 and more
"*Financials for private companies would be provided on a best efforts basis”.
LIST OF TABLES
1.Global Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)1.1 Liver Organoids Market 2019-2024 ($M) - Global Industry Research
1.2 Liver-On-A-Chip Market 2019-2024 ($M) - Global Industry Research
1.3 2D Model Market 2019-2024 ($M) - Global Industry Research
1.4 Animal Model Market 2019-2024 ($M) - Global Industry Research
1.5 3D Bioprinting Market 2019-2024 ($M) - Global Industry Research
2.Global Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 (Volume/Units)
2.1 Liver Organoids Market 2019-2024 (Volume/Units) - Global Industry Research
2.2 Liver-On-A-Chip Market 2019-2024 (Volume/Units) - Global Industry Research
2.3 2D Model Market 2019-2024 (Volume/Units) - Global Industry Research
2.4 Animal Model Market 2019-2024 (Volume/Units) - Global Industry Research
2.5 3D Bioprinting Market 2019-2024 (Volume/Units) - Global Industry Research
3.North America Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)
3.1 Liver Organoids Market 2019-2024 ($M) - Regional Industry Research
3.2 Liver-On-A-Chip Market 2019-2024 ($M) - Regional Industry Research
3.3 2D Model Market 2019-2024 ($M) - Regional Industry Research
3.4 Animal Model Market 2019-2024 ($M) - Regional Industry Research
3.5 3D Bioprinting Market 2019-2024 ($M) - Regional Industry Research
4.South America Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)
4.1 Liver Organoids Market 2019-2024 ($M) - Regional Industry Research
4.2 Liver-On-A-Chip Market 2019-2024 ($M) - Regional Industry Research
4.3 2D Model Market 2019-2024 ($M) - Regional Industry Research
4.4 Animal Model Market 2019-2024 ($M) - Regional Industry Research
4.5 3D Bioprinting Market 2019-2024 ($M) - Regional Industry Research
5.Europe Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)
5.1 Liver Organoids Market 2019-2024 ($M) - Regional Industry Research
5.2 Liver-On-A-Chip Market 2019-2024 ($M) - Regional Industry Research
5.3 2D Model Market 2019-2024 ($M) - Regional Industry Research
5.4 Animal Model Market 2019-2024 ($M) - Regional Industry Research
5.5 3D Bioprinting Market 2019-2024 ($M) - Regional Industry Research
6.APAC Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)
6.1 Liver Organoids Market 2019-2024 ($M) - Regional Industry Research
6.2 Liver-On-A-Chip Market 2019-2024 ($M) - Regional Industry Research
6.3 2D Model Market 2019-2024 ($M) - Regional Industry Research
6.4 Animal Model Market 2019-2024 ($M) - Regional Industry Research
6.5 3D Bioprinting Market 2019-2024 ($M) - Regional Industry Research
7.MENA Human Liver Model Market, By Drug Discovery Platform Market 2019-2024 ($M)
7.1 Liver Organoids Market 2019-2024 ($M) - Regional Industry Research
7.2 Liver-On-A-Chip Market 2019-2024 ($M) - Regional Industry Research
7.3 2D Model Market 2019-2024 ($M) - Regional Industry Research
7.4 Animal Model Market 2019-2024 ($M) - Regional Industry Research
7.5 3D Bioprinting Market 2019-2024 ($M) - Regional Industry Research
LIST OF FIGURES
1.US Human Liver Models Market Revenue, 2019-2024 ($M)2.Canada Human Liver Models Market Revenue, 2019-2024 ($M)
3.Mexico Human Liver Models Market Revenue, 2019-2024 ($M)
4.Brazil Human Liver Models Market Revenue, 2019-2024 ($M)
5.Argentina Human Liver Models Market Revenue, 2019-2024 ($M)
6.Peru Human Liver Models Market Revenue, 2019-2024 ($M)
7.Colombia Human Liver Models Market Revenue, 2019-2024 ($M)
8.Chile Human Liver Models Market Revenue, 2019-2024 ($M)
9.Rest of South America Human Liver Models Market Revenue, 2019-2024 ($M)
10.UK Human Liver Models Market Revenue, 2019-2024 ($M)
11.Germany Human Liver Models Market Revenue, 2019-2024 ($M)
12.France Human Liver Models Market Revenue, 2019-2024 ($M)
13.Italy Human Liver Models Market Revenue, 2019-2024 ($M)
14.Spain Human Liver Models Market Revenue, 2019-2024 ($M)
15.Rest of Europe Human Liver Models Market Revenue, 2019-2024 ($M)
16.China Human Liver Models Market Revenue, 2019-2024 ($M)
17.India Human Liver Models Market Revenue, 2019-2024 ($M)
18.Japan Human Liver Models Market Revenue, 2019-2024 ($M)
19.South Korea Human Liver Models Market Revenue, 2019-2024 ($M)
20.South Africa Human Liver Models Market Revenue, 2019-2024 ($M)
21.North America Human Liver Models By Application
22.South America Human Liver Models By Application
23.Europe Human Liver Models By Application
24.APAC Human Liver Models By Application
25.MENA Human Liver Models By Application