Metagenomics Market - Forecast(2024 - 2030)

Metagenomics Market size is estimated to reach $1.5 billion by 2027, growing at a CAGR of 16.2% during the forecast period 2022-2027. Metagenomics is the examination of genetic material reclaimed directly from environmental samples. The expansive field may also be specified as environmental genomics, eco-genomics or community genomics. Shotgun metagenomic sequencing is a comparatively novel environmental sequencing technique utilized to analyze thousands of organisms in parallel and completely sample all genes, offering acumen into community biodiversity and function. 16S rRNA gene sequencing is typically restricted to recognizing bacteria at the genus level (e.g. Bifidobacteria). De novo assembly has been a necessary instrument in current investigations in metagenomics viral analysis. Glycoside hydrolases (GHs) are amidst the industrially significant enzymes that are widely explored by way of metagenomics owing to their very great expedience and significance in food and additional industrial sectors. Whole-genome sequencing offers added information on the nature and localization of antimicrobial resistance factors and on their dissemination possibility by horizontal gene delivery, and on genes connecting to virulence and biological fitness. Interoperable data will play a principal role in the forthcoming utilization of whole genome sequencing and metagenomic data.

The COVID-19 pandemic is set to drive the Metagenomics Market owing to the extensive utilization of technologies like Metagenomics in pandemic hazard computations to detect the molecular alterations in pathogens at the time of their worldwide rise, which could help in the forecast of rising hotspots, populations at risk, and the pathogens under genetic evolution as per the research article issued in Future Science, 2021. The burgeoning interest of researchers in related new research fields like metatranscriptomics, metaproteomics, and metabolomics has inspired microbiologists to investigate related workflows` in conjunction with novel techniques like shotgun metagenomic sequencing and is set to propel the growth of the Metagenomics Market during the forecast period 2022-2027. This represents the Metagenomics Industry Outlook.

Report Coverage

The report: “Metagenomics Market Forecast (2022-2027)”, by Industry ARC, covers an in-depth analysis of the following segments of the Metagenomics Market.

By Product: Sequencing And Data Analytics Services, Kits And Reagents, Others.
By Technology: Sequencing Driven, Function Driven.
By Application: Human Health, Environmental, Others.
By Geography: North America (the U.S, Canada, and Mexico), South America (Brazil, Argentina, Chile, Colombia, Rest of South America), Europe (Germany, France, UK, Italy, Spain, Russia, and Rest of Europe), Asia-Pacific (China, Japan, South Korea, India, Australia & New Zealand, and Rest of Asia-Pacific), and Rest Of The World (Middle East, Africa). 

Key Takeaways

• Geographically, North America Metagenomics Market accounted for the highest revenue share in 2021 and it is poised to dominate the market over the period 2022-2027 owing to the existence of a soaring count of pharmaceutical and biotechnological firms developing new and effective metagenomic platforms in conjunction with novel techniques like shotgun metagenomic sequencing in the North American region.
• Metagenomics Market growth is being driven by the technological advancements in DNA sequencing in conjunction with the development of novel techniques like shotgun metagenomic sequencing. However, the soaring cost of complete metagenomics is one of the major factors hampering the growth of the Metagenomics Market.
• Metagenomics Market Detailed Analysis on the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Metagenomics Market report. 
  
  

  Metagenomics Market Share, By Product, 2021(%)
  

  
  

Metagenomics Market Segment Analysis – By Product:

The Metagenomics Market based on products can be further segmented into Sequencing And Data Analytics Services, Kits And Reagents, and Others. The Kits And Reagents Segment held the largest market share in 2021. This growth is owing to the considerable count of kits and reagents being introduced and utilized to back the increasing demand for library preparation workflows from research laboratories. The boost in the rate of application and the great infiltration in conjunction with the extensive application of shotgun metagenomic sequencing is further propelling the growth of the genome engineering segment.

Furthermore, the Sequencing And Data Analytics Services segment is estimated to grow with the fastest CAGR of 16.9% during the forecast period 2022-2027 owing to the accelerated and considerable cost minimization in next-generation sequencing which has productively expedited the growth of sequence-based metagenomics in conjunction with the soaring application of shotgun metagenomic sequencing.

Metagenomics Market Segment Analysis – By Technology:

The Metagenomics Market based on technology can be further segmented into Sequencing Driven and Function Driven. The Sequencing Driven Segment held the largest market share in 2021. This growth is owing to the soaring application of this technology. The burgeoning acceptance of this technology may be ascribed to the onset of new bioinformatics-associated solutions, which make workflows easy and offers accelerated outcomes. shotgun metagenomic sequencing permits researchers to exhaustively sample all genes in all organisms existing in a given complex sample. Surging endeavors to keep up a standard database and increase in the count of metagenome samples accumulated at data repositories are further propelling the growth of this segment.

Furthermore, the Function Driven segment is estimated to grow with the fastest CAGR of 17.1% during the forecast period 2022-2027 owing to the increasing application of function-driven metagenomics for protein screening applied to antibiotic resistance and vitamin manufacture in conjunction with the proliferating application of shotgun metagenomic sequencing.

Metagenomics Market Segment Analysis – By Geography:

The Metagenomics Market based on geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America (Metagenomics Market) held the largest share with 36% of the overall market in 2021. The growth of this region is owing to the surging spend on R&D. The extensive acceptance of metagenomic diagnostic, an expanding count of next-generation sequencing(NGS) based research endeavors in conjunction with increased application of shotgun metagenomic sequencing and the existence of key players like Illumina Inc., in the region are propelling the growth of the Metagenomics market in the North American region.

Furthermore, the Asia-Pacific region is estimated to be the region with the fastest CAGR rate over the forecast period 2022-2027. This growth is owing to factors like consistent developments performed to build up the bioinformatics infrastructure and genomic landscape in nations like India and China. The considerable fluctuation in climate and environment in the region together with the heightening application of shotgun metagenomic sequencing is fuelling the progress of the Metagenomics market in the Asia-Pacific region.

Metagenomics Market Drivers

Increased Application Of Shotgun Metagenomic Sequencing Is Projected To Drive The Growth Of Metagenomics Market:

Shotgun metagenomic sequencing developed by Illumina Inc., permits researchers to completely sample all genes in all organisms existing in a given complex sample. The technique allows microbiologists to assess bacterial diversity and discover the profusion of microbes in different environments. Shotgun metagenomics also offers a means to investigate unculturable microorganisms that are otherwise hard or impossible to evaluate. Unlike capillary sequencing or PCR-based techniques, next-generation sequencing (NGS) permits researchers to sequence thousands of organisms in parallel. With the capability to integrate abundant samples in a single sequencing run and acquire high sequence coverage per sample, NGS-based metagenomic sequencing can discover very low abundance members of the microbial community that may be unnoticed or are too high-priced to recognize utilizing additional techniques. The surging application of shotgun metagenomic sequencing is fuelling the growth of the Metagenomics Market during the forecast period 2022-2027.

Benefits Of 16S rRNA Sequencing Are Expected To Boost The Demand Of Metagenomics:

16S rRNA Sequencing is a typical amplicon sequencing technique utilized to recognize and compare bacteria existing within a given sample. The prokaryotic 16S rRNA gene is almost 1500 bp long, with nine variable regions integrated between conserved regions. Variable regions of the 16S rRNA gene are generally utilized for the phylogenetic classification of genus or species in different microbial populations. An essential advantage of 16S rRNA Sequencing is that it offers an affordable method to recognize strains that may not be discovered utilizing conventional techniques. Unlike capillary sequencing or PCR-based techniques, next-generation sequencing (NGS) is a culture-free technique that allows investigation of the complete microbial community within a sample. 16S rRNA NGS permits microbiologists to accomplish genus-level sensitivity for metagenomic examinations of bacterial populations. The advantages of 16S rRNA Sequencing are driving the growth of the Metagenomics Market during the forecast period 2022-2027.

Metagenomics Market Challenges

Databases For Metagenomic Data Present Challenges To The Growth Of The Metagenomics Market:

Absorbing the sequence that will be produced by metagenomics projects will be demanding for the nucleic acid sequence data archive. Adding to the archiving challenge, it is evident that the community will need novel, secondary databases if the data are to be utilized efficiently. Only a specially-designed database will be able to provide constant storage and querying of the abundant metadata that metagenomic sequences require. The investigation of metagenomic sequences will need computational programs that are best provided in the context of a specially-designed database, for example, programs for the clustering of metagenomic sequence reads or for time-series analysis. And metagenomic data must be combined with data from distinct projects, like satellite data on ocean temperatures and time-series data on alterations in ocean salinity. This issue is hampering the growth of the Metagenomics Market.

Metagenomics Market Landscape:

Product launches, technological advancements, collaborations, mergers and acquisitions, financing in R&D activities, partnerships, and joint ventures are key strategies adopted by players in this Market. Metagenomics top 10 companies include:

1. Thermo Fisher Scientific, Inc.
2. QIAGEN
3. Illumina, Inc.
4. Promega Corporation
5. Novogene Co., Ltd.
6. Takara Bio, Inc
7. Oxford Nanopore Technologies
8. Arc Bio, LLC.
9. Eurofins Scientific
10. Zymo Research

Acquisitions/Product Launches:

• In November 2021, QIAGEN declared the inclusion of StableScript™ to the OEM portfolio. The versatile reverse transcriptase is planned for application in one-step RT-qPCR and long-range RT-PCR and is accessible to order in bulk amounts. The launch of reverse transcriptases has permitted polymerase chain reaction (PCR) to be adapted to RNA and the establishment of cDNA libraries from mRNA.
• In October 2021, QIAGEN N.V. declared the introduction and CE marking of QIAreach® QuantiFERON®-TB test for tuberculosis (TB) infection, to assist in accomplishing TB removal targets worldwide by boosting access to effortless and trustworthy TB testing, specifically in great burden countries, low-resource regions. A breakthrough in the battle against a pathogen estimated to be carried by over two billion people globally established on the proven QuantiFERON-TB Gold Plus technology, QIAreach® QuantiFERON®-TB is a portable instrument that allows the ultrasensitive digital discovery of TB infection with an end-to-end workflow that is clear and cost-efficient and raises access to trustworthy Interferon Gamma Release Assay (IGRA) testing. QIAGEN will target regions that encounter a huge burden of the ailment, and where procuring access to laboratory infrastructure and resources for testing is restricted.
• In July 2021, QIAGEN N.V. declared the introduction of the Workflow Configurator, allowing researchers in the life sciences to effortlessly and speedily discover the best solutions to make their experiments perfect. Purchasers simply select their application, biological starting material, analyte, and analysis type. In seconds, the configurator arranges by way of hundreds of possible products to detect the most appropriate workflow and related products.

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