Increasing Usage of Polysorbates as a Stabilizing Agent Is Anticipated To Drive Polysorbate in Bophirima Market During The Forecast Period. Polysorbate in Biopharma Market size market was estimated at $112.4 million in 2020, growing at a CAGR of 7.2% during the forecast period 2021-2026.
Increasing usage of polysorbate as a stabilizing agent in biopharmaceutical industry is a vital factor driving Polysorbate in Biopharma market. Moreover, upsurge in use of polysorbate for inhibition of protein aggregation is a vital factor contributing to its market growth. Furthermore Polysorbates are prominently used surfactants in biopharmaceutical formulations especially as protein stabilizers to prevent proteins from aggregation, denaturation, flocculant formulation, and surface adsorption during the thaw. Polysorbate 80 is an excipient used to stabilise aqueous Biopharmaceutical formulations for parenteral administration or vaccinations. Polysorbate is used as a lubricant in ocular solutions and as an excipient in Biopharmaceutical products to stabilise emulsions and suspensions.
Polysorbates are a nonionic surfactant and emulsifier that are frequently utilised in biopharmaceutical applications due to their nontoxicity, ease of access, emulsification, and solubilization qualities. There are two types of Polysorbates such as polysorbate 20 and polysorbate 80. Polysorbate 20, often known as Tween 20, is a nonionic surfactant made from sorbitol, a natural sugar alcohol, and is formed by ethoxylation of sorbitan followed by the addition of lauric acid. It is widely used to reduce protein denaturation and aggregation in therapeutic monoclonal antibodies (mAb). Polysorbate 80 is a nonionic synthetic surfactant used in biopharmaceutical preparations as an excipient. Some of the drugs manufactured with polysorbate 80 are docetaxel, epoetin/darbepoetin, and fosaprepitan, which are used in cancer for chemotherapy, supportive care, or prevention. Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medicine for parenteral administration or vaccinations.
North America holds a major share of Polysorbate in Biopharma market owing to trends of the favorable factors in this region and has a presence of a large number of manufacturers in the U.S., and the increasing research and development expenses by the manufacturers in developing new drugs is helping in the growth of cancer monoclonal antibodies in this country, is also estimated to boost the market. In U.S. many vaccination used, notably the Janssen COVID-19 vaccine, contain polysorbate 80. It is utilised in the Middlebrook 7H9 broth culture of Mycobacterium tuberculosis. Estrasorb, an estrogen-regulating medication, contains it as an emulsifier. It's also play the role of emulsifier, which aids in the mixing of materials and the prevention of separation, as well as a water-containing small amounts of salts, and it's found in a number of vaccines approved in the United States. Moreover, rising usage of polysorbate in oncology drugs in this region is driving the growth of polysorbate in biopharma market. In Canada it is estimated that 220,400 new cases of cancer will be diagnosed by the end of 2021. The number of cancer cases diagnosed each year has been increasing owing to growing and ageing population and the current lifestyle. It is expected that 90% of new cases will be diagnosed in individuals of 50 years of age and older which increases the growth of market in this region. Rising demand of polysorbate from the scientists for future research is also predicted to drive new growth opportunities for Polysorbate in Biopharma Market during 2021-2026.
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Polysorbate in Biopharma Market Growth Drivers:
Increasing Demand for Polysorbates in COVID-19 Vaccines.
Increasing demand for polysorbate in COVID-19 vaccines owing to its function as excipient and as a solubilizing agent also contribute abetting the growth of the market. For instance, Oxford-AstraZeneca vaccine contain ChAdOx1-S recombinant, L-histidine, L-histidine hydrochloride monohydrate, magnesium chloride hexahydrate, polysorbate 80, ethanol, sucrose, sodium chloride, disodium edetate dihydrate, water for injections. This increases the growth of Polysorbate in Biopharma Market.
Growing Usage of polysorbate in Oncology drugs:
Growing usage of polysorbate in oncology drugs is increasing the growth of polysorbate in biopharma market. Polysorbate 80 is a nonionic synthetic surfactant used as an excipient in Biopharmaceutical preparation. Some of the drugs manufactured with polysorbate 80 are docetaxel, epoetin/darbepoetin, and fosaprepitant, used in cancer treatment for chemotherapy, supportive care, or prevention also increases the growth of Polysorbate in Biopharma Market.
Rising Demand Of Polysorbate To Prevent Aggregation Of Protein:
Increasing demand of polysorbate to prevent aggregation of protein is driving the growth of polysorbate in biopharma market. Moreover, Polysorbates are commonly used in protein therapy drugs used to reduce adsorption and aggregation on the surface. Polysorbate is commonly used to prevent protein aggregation, possibly via lowering protein accumulation and subsequent aggregation at the interface thereby increasing the growth of Polysorbate in Biopharma Market.
The Major Players in this Market Include
The major companies in Polysorbate in Biopharma Market include Lonza, Avantor Inc., Merck KGaA, NOF Corporation, Thermo Fisher Scientific Inc., Guangdong Runhua Chemistry Co., Ltd., Aceto Corporation, Seppic SA, Croda International plc., and Nanjing Well Biopharmaceutical Co. ltd.
In April 2021, Lonza signed agreement with aTyr Pharma, Inc. for the manufacture of ATYR2810, aTyr's monoclonal antibody targeting Neuropilin-2 (NRP2).
Over the years, companies have mainly focused on research and development and have been investing in developing various drugs. The technological advancement in research and development driving the Polysorbate in Biopharma market during 2021-2026.
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