HLA Typing for Transplant Market by Technology (SSO-PCR, SSP-PCR, NGS, Sanger Sequencing), Products & Services (Instruments, Reagents, Software), Application (Diagnostics, Research), End User (Hospitals, Academia, Diagnostic Center) - Forecast to 2021 - 2026

Report Code: HCR 0545 Report Format: PDF + Excel

HLA Typing for Transplant Market Overview

The HLA typing for transplant market is estimated to reach $1,136 million by 2026 and is poised to grow at a CAGR of 7.4% over the forecast period of 2021-2026. HLA or Human Leukocyte antigen is a common protein antigen inherited from the parental generation. A person would receive six-vital HLA, three from both the parents. The antigens have been coded as A2, A30, B8, B70, DR3, and DR8. Antigens are the markers present in one’s body, which helps one distinguish from the other human being. The typing/matching test is prevalent to avoid complications such as graft versus host disease, which is caused when the body tries to eliminate the graft and the immune response or WBCs are set to counter it as one of the viruses or bacteria. Moreover, major histocompatibility complex owing to GVHD, doctors are preferring cord blood transplants as the chances reduce by up to 50%. Moreover, transplant diagnostics have to be run in order to find out any form of virus or immuno-acquired diseases, which have the potential to prove fatal to the recipient.

The increasing number of organ transplants and the associated technology along with the rising geriatric population are some of the factors driving the HLA typing for the transplant industry forward in the projected period of 2021-2026.

Report Coverage

The report: “HLA Typing for Transplant Market Forecast (2021-2026)”, by Industry ARC covers an in-depth analysis of the following segments of the HLA typing for the transplant market.

By Technology- Molecular Assay Technologies and Non-Molecular Assay Technologies
By Products and Services- Reagents and Consumables, Instruments, Software and Services
By Application- Diagnostic Application, Research Applications, and Others
By End Users – Independent Reference Laboratories, Hospital and Transplant Center, and Research Laboratories & Academic Institutes.
By Geography- North America (U.S., Canada, Mexico), Europe (Germany, United Kingdom (U.K.), France, Italy, Spain, Russia, and Rest of Europe), Asia Pacific (China, Japan India, South Korea, Australia, and New Zealand, and Rest of Asia Pacific), South America (Brazil, Argentina, and Rest of South America), and Rest of the World (the Middle East, and Africa).

Key Takeaways

  • Geographically, North America’s HLA typing for transplant held a dominant market share in the year 2020. It is owing to the advent and adoption of technologically advanced tools and products which have eased the entire process. However, Asia-Pacific offers lucrative opportunities to the marketers owing to the rising geriatric population and increased expenditure for realizing better healthcare infrastructure.
  • A rising geriatric population along with their tendency of having transplants has been recognized as a ready driver for the market. However, the high costs associated with and chances of developing GVHD has acted as a grave market challenge.
  • A detailed analysis of the strengths, weaknesses, opportunities, and threats will be provided in the HLA typing for transplant market report. 

HLA Typing for Transplant Market Share, By Technology, 2020(%)

HLA Typing for Transplant Market
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HLA Typing for Transplant Market Segmentation Analysis- By Technology

The HLA typing for the transplant market based on technology can be further segmented into molecular assay and non-molecular assay technologies. The molecular assay technology dominated the market in the year 2020. It is owing to the high efficacy and low error rate of the following technology. PCR tests readily help recognize the pathogens or antigens present in the sample, and due to their various sizes (desk and standing), laboratories and various end-users have preferred them over the others.

Moreover, molecular assay technology is estimated to be the fastest-growing, with a CAGR of 7.9% over the forecast period of 2021-2026. It is owing to the recent advancements in the industry after the pandemic struck, and the heavy usage of PCR tests to detect the Sars Antigen forced the innovators to look for more sustainable machines which can be a hybrid module and would allow them to move forward after the pandemic ends. Additionally, PCR technology can deliver qualitative and quantitative results within a day or hours after the sample collection.

HLA Typing for Transplant Market Segmentation Analysis- By End Users

The HLA typing for the transplant market based on end-users can be further segmented into Independent Reference Laboratories, Hospital and Transplant Center, and Research Laboratories & Academic Institutes. The hospital and transplant segment held a dominant market share in the year 2020. It is owing to the multiple specialty hospitals catering to varied demands and having established in-house testing facilities to smooth the entire process. For example, Medical City Dallas has grown out to be the fastest-growing transplant center and has grown by about 310% in three years.

Further, the hospital and transplant center is estimated to be the fastest-growing, with a CAGR of 8.1% over the forecast period of 2021-2026. It is owing to the rising number of chronic kidney diseases across the world owing to cardiovascular diseases such as diabetes. As per CDC, 1 in 3 people is at risk of developing such diseases, and there are more than 100,000 people on the waiting list for such transplants. The following would augment the growth of the HLA typing for the transplant market in the projected period.

HLA Typing for Transplant Market Segmentation Analysis- By Geography

The HLA typing for the transplant market based on Geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America’s HLA typing for transplant market held a dominant market share of 37% over the others. It is owing to the ready deployment of the latest technologies which brings down the fatalities. Moreover, the government spending on healthcare in the region is by far the highest as compared to other geographies, which has resulted in increased R&D activities. As per the CDC, the US spends $11,582 per person, and the share of healthcare spending is close to 17.7% of the entire GDP.

However, Asia-Pacific offers lucrative opportunities to marketers. It is owing to the rising concerns of government and private bodies to improve medical conditions. To fulfill those commitments, the region has seen an increase in healthcare spending over the last decade. Countries such as Korea and Japan have been the pioneer of healthcare technology and the introduction of IoT in various deployments. Additionally, India saw a 137% rise in healthcare spending from 2019. Such developments across the region will help in the growth of the HLA typing for the Transplant market in the projected period of 2021-2026.

HLA Typing for Transplant Market Drivers

The advent of the latest technology has readily supplanted the HLA typing for the transplant market.

The use of UCB or Umbilical cord blood in place of bone marrow has helped the market. It is owing to the former’s ability to provide better results than the latter. Additionally, as per various research, the use of cord blood can reduce the chances of developing GVHD or graft versus host disease to less than 10%, which for bone marrow stands at 60%. Additionally, it is found that cord blood transplants have a lower potency of developing tumors over a lifetime, and the chance of viral contamination is low. Moreover, the following allows for high cell proliferation capacity. The use of HLA typing or matching can further progress the use of the UCB in un-related or racial or ethical minorities whose genetic variations are not yet registered in the feed. The following advent has helped in the growth of the market.

The rising number of geriatric patients will assist the demand for HLA typing.

As per the US Healthcare and Human Services, most of the patients needing a transplant have been in the age bracket above 50 years or were above 64 years. It is owing to the natural tendency of the organs to stop functioning healthy after a sedentary lifestyle and other cardiovascular ailments like diabetes. Additionally, the US CDC projects a boom in the geriatric population in the fore coming times and period. As per them, by 2034, the young adults and those above 65+ will break even and there would be a ready demand for better and advanced technology to assist them during transplants and other ailments.

HLA Typing for Transplant Market Challenges

The cases of severe GVHD have dampened the confidence in HLA typing and have acted as a grave market challenge.

The incidence of severe or moderate GVHD has been rising in the 7MM. Moreover, epidemiologists have associated various factors which have resulted in the prevalence of the disease by up to 70%. Donor recipient parity or low gene antigen matching and graft source have been attributed as the “primary reason.” Additionally, GVHD arises when the patient's (recipient’s) body attacks the graft given by the donor, as it identifies it as the potential threat from a foreign substance; cases of fatality have been recorded in occurrences of allogeneic stem cell transplantation. However, the researchers are trying to find the early stages at which the disease’s severity can be dampened.

HLA Typing for Transplant Market Competitive Landscape

Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the HLA typing for transplant market. The top 10- HLA typing for transplant market companies include:

  1. Thermo Fisher Scientific, Inc.
  2. QIAGEN N.V, I
  3. llumina
  4. CareDx, Inc.
  5. Immucor, Inc.
  6. Bio-Rad Laboratories, Inc.
  7. F. Hoffman-La Roche Ltd.
  8. Hologic, Inc.
  9. Luminex
  10. Biofortuna

HLA Typing for Transplant Market Developments

  • In November 2019, Thermo Fischer Scientific introduced their “Ion Torrent Genexus System.” The system is a fully integrated next-gen sequencing platform that would allow for the automated specimen to reporting workflow in a single day. Further, the company’s aim is to enable the local hospitals to adapt to the NGS testing feature. 
  • In March 2019, QuantuMDx had developed a novel, low-cost sample which allows the users/hospitals to use the molecular diagnostics technology at both low and high levels. Additionally, the device is capable of handling qPCR and end-PCR with a help of micro-array. Additionally, the test guarantees result within 30 minutes which will help in screening more individuals. 

Relevant Titles:

Report Code- HCR 0011

Report Code- HCR 0137 

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1. HLA Typing for Transplant Market- Overview
    1.1 Definitions and Scope
2. HLA Typing for Transplant Market- Executive Summary
    2.1 Market Revenue, Market Size and Key Trends
    2.2 Key trends by Technology
    2.3 Key trends by Application
    2.4 Key trends by Geography
3. HLA Typing for Transplant Market- Comparative Analysis
    3.1 Company Benchmarking – Key Companies
    3.2 Financial Analysis– Key Companies
    3.3 Market Share Analysis– Key Companies
    3.4 Patent Analysis
    3.5 Pricing Analysis- Average Selling Price
4. HLA Typing for Transplant Market- Startup Companies Scenario Premium
    4.1 Key Startup Company Analysis by
        4.1.1 Investment
        4.1.2 Revenue
        4.1.3 Venture Capital and Funding Scenario
5. HLA Typing for Transplant Market– Industry Market Entry Scenario Premium Premium
    5.1 Regulatory Framework Overview
    5.2 New Business and Ease of Doing Business Index
    5.3 Case Studies of Successful Ventures
6. HLA Typing for Transplant Market- Forces
    6.1 Market Drivers
    6.2 Market Constraints/Challenges
    6.3 Porters Five Force Model
        6.3.1 Bargaining power of suppliers
        6.3.2 Bargaining powers of customers
        6.3.3 Threat of new entrants
        6.3.4 Rivalry among existing players
        6.3.5 Threat of substitutes
7. HLA Typing for Transplant Market– Strategic Analysis
    7.1 Value Chain Analysis
    7.2 Opportunities Analysis
    7.3 Market Life Cycle
8. HLA Typing for Transplant Market– By Technology (Market Size –$Million/$Billion)
    8.1 Molecular Assay Technologies
        8.1.1 PCR Based Molecular Assays
            8.1.1.1 Real Time PCR
            8.1.1.2 Sequence Specific Primer PCR
            8.1.1.3 Sequence Specific Oligonucleotide PCR
            8.1.1.4 Other PCR based Molecular Assays
        8.1.2 Sequencing Based Molecular Assays
            8.1.2.1 Sanger Sequencing
            8.1.2.2 Others.
    8.2 Non-Molecular Assay Technologies
9. HLA Typing for Transplant Market– By Products and Services (Market Size –$Million/$Billion)
    9.1 Reagents and Consumables
    9.2 Instruments
    9.3 Software & Services
10. HLA Typing for Transplant Market– By Application (Market Size –$Million/$Billion)
    10.1 Diagnostic Application 
    10.2 Research Applications
    10.3 Others 
11. HLA Typing for Transplant Market– By End Users (Market Size –$Million/$Billion)
    11.1 Independent Reference Laboratories
    11.2 Hospital and Transplant Centers
    11.3 Research Laboratories and Academic Institutes
12. HLA Typing for Transplant Market- By Geography (Market Size –$Million/$Billion)
    12.1 North America
        12.1.1 U.S.
        12.1.2 Canada
        12.1.3 Mexico
    12.2 Europe
        12.2.1 U.K.
        12.2.2 Germany
        12.2.3 France
        12.2.4 Italy
        12.2.5 Spain
        12.2.6 Russia
        12.2.7 Rest of Europe
    12.3 Asia-Pacific
        12.3.1 China
        12.3.2 India
        12.3.3 Japan
        12.3.4 South Korea
        12.3.5 Australia & New Zealand
        12.3.6 Rest of Asia-Pacific
    12.4 South America
        12.4.1 Brazil
        12.4.2 Argentina
        12.4.3 Rest of South America
    12.5 Rest of the World
        12.5.1 Middle East
        12.5.2 Africa
13. HLA Typing for Transplant Market- Entropy
14. HLA Typing for Transplant Market– Industry/Segment Competition Landscape Premium 
    14.1 Market Share Analysis
        14.1.1 Global Market Share – Key Companies
        14.1.2 Market Share by Region – Key companies
        14.1.3 Market Share by Countries – Key Companies
        14.1.4 Competition Matrix
        14.1.5 Best Practices for Companies
15. HLA Typing for Transplant Market– Key Company List by Country Premium Premium
16. HLA Typing for Transplant Market Company Analysis
    16.1 Company 1
    16.2 Company 2
    16.3 Company 3
    16.4 Company 4
    16.5 Company 5
    16.6 Company 6
    16.7 Company 7
    16.8 Company 8
    16.9 Company 9
    16.10 Company 10
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