Enterovirus Diagnostics Market Overview
Enterovirus Diagnostics Market Size is estimated to reach $7.8 billion by 2027
. Furthermore, it is poised to grow at a CAGR of 6.9%
over the forecast period of 2022-2027. Enteroviruses are single-stranded ribonucleic acid (RNA) viruses that are tiny and contagious and are linked to a variety of human and mammalian diseases. Poliovirus, coxsackievirus, echovirus, and enterovirus are among the 12 species in the enterovirus genus, which have four primary serotypes: poliovirus, coxsackievirus, echovirus, and enterovirus. The recently discovered enteroviruses are given numbers starting with EV68, EV69, EV70, and so on. Enteroviruses are one of the most frequent human viruses, infecting over one billion people each year, the majority of whom are newborns and children. Aorta intramural hematoma (IMH), usually results from bleeding into the aortic wall from the vasa vasorum without an intimal tear, is an unusual form of aortic dissection. Along with penetrating atherosclerotic ulcer (PAU) and typical aortic dissection, it is a subset of the acute aortic syndrome. Different varieties of enteroviruses cause diseases such as polio, meningitis, pancreatitis, hepatitis, encephalitis, hand, foot, and mouth disease; birth abnormalities, attention deficit hyperactivity disorder, intramural hematoma, and cardiac disorders. These viruses are transmitted from person to person either directly or indirectly through the fecal-oral channel, the respiratory route, and even from mother to infant during the peripartum period. More than half of all enterovirus infections are asymptomatic. The infected person experiences mild symptoms such as a cold and fever and is also able to create can create complications in individuals with health conditions such as pneumonia, brain diseases, and heart conditions. As a result, diagnosing this infection is tough, but technological advancements in diagnostic methods such as polymerase chain reaction tests, and serology testing made it easier. Inflammatory alterations in the cerebrospinal fluid (CSF), such as pleocytosis, and the presence of the virus, which may be determined using polymerase chain reaction
test analysis (PCR), are used to identify enterovirus-induced meningitis. Pharmaceutical companies are concentrating their efforts on preventing viral infections from spreading. Twist Bioscience, a DNA manufacturer, for example, announced a new research panel in June 2020 to assess the increased occurrence of viruses such as coronaviruses, enteroviruses, rhinoviruses, and other respiratory tract viral disorders using next-generation sequencing. These factors are anticipated to grow Enterovirus Diagnostics Industry over the forecast period 2022-2027.
Enterovirus Diagnostics Market Report Coverage
The report: “Enterovirus Diagnostics Market Forecast (2022-2027)", by Industry ARC covers an in-depth analysis of the following segments of the Enterovirus Diagnostics Market.
By Testing Technology: Viral Isolation Testing, Serology testing, PCR assay, and Others.
By End User: Hospitals, Commercial or Private Laboratories, Public Health Laboratories, and Others.
By Geography: North America (U.S., Canada, Mexico), Europe (Germany, United Kingdom (U.K.), France, Italy, Spain, Russia, and the Rest of Europe), Asia Pacific (China, Japan India, South Korea, Australia, and New Zealand, and Rest of Asia Pacific), South America (Brazil, Argentina, Chile, Colombia and Rest of South America), and Rest of the World (the Middle East, and Africa).
- Geographically, North America held a dominant market share in the year 2021, owing to advanced health infrastructure in countries like the United States and Canada fuel the growth of Enterovirus Diagnostics Market Size in this region.
- The Enterovirus Diagnostics Market is predicted to increase owing to the increasing number of the adolescent population, currently 1.3 billion adolescents in the world in 2022 as per UNICEF.
- However, the high cost of equipment may limit market growth over the forecast period 2022-2027.
- A detailed analysis of strengths, weaknesses, opportunities, and threats will be provided in the Enterovirus Diagnostics Market Report.
Enterovirus Diagnostics Market: Market Share (%) by Region, 2021
Enterovirus Diagnostics Market Segmentation Analysis- By Testing Technology
Enterovirus Diagnostics Market based on technology can be further segmented into Viral Isolation Testing, Serology testing, PCR assay, and Others. PCR segment held a dominant market share in the year 2021 and is estimated to grow with the fastest CAGR rate of 8.5% over the forecast period 2022-2027. Owing to the increased use in clinical diagnostics, rising demand for personalized and precision medicine, and technical advances and applications in drug development. A polymerase chain reaction test (PCR) sensitivity level can be as low as a single organism, allowing for the detection of enterovirus in cerebral spinal fluid specimens such as cerebrospinal fluid, with a sensitivity of 100%. The viruses in the EV D68 outbreak were identified using this test on a nasopharyngeal swab collected from cold patients with the fast results of PCR technology. High accuracy and sensibility of polymerase chain reaction test (PCR) in the detection of enterovirus help to fuel the Enterovirus Diagnostics Market Share over the forecast period 2022-2027.
Enterovirus Diagnostics Market Segmentation Analysis- By End User
Enterovirus Diagnostics Market based on end-user can be further segmented into Hospitals, Commercial or Private Laboratories, Public Health Laboratories, and Others. The Hospital segment held a dominant market share in the year 2021. This is owing to the use of improved diagnostic technology over time in hospitals. The majority of hospitals have their clinical laboratories or tie-up. In such clinical laboratories, the diagnostic of enterovirus is possible owing to advanced techniques like PCR assay, Viral Isolation testing, and Serology testing methods for enterovirus diagnostics which fuel the market growth of the Enterovirus Diagnostics Market Share.
However, Commercial or Private laboratories are estimated to grow with the fastest CAGR rate of 7.4% over the forecast period 2022-2027. This can be owed to the increasing number of private diagnostic laboratories across the globe and reliable techniques used for diagnostic specific lab tests on specimens from a person's nose and throat, or unique testing on blood or spinal fluid or cerebrospinal fluid, as well as MRI findings have been employed. The use of this technology shows higher results for enterovirus detection which helps to grow the Enterovirus Diagnostics Market Share over the forecast period.
Enterovirus Diagnostics Market Segmentation Analysis- By Geography
The Enterovirus Diagnostics Market based on Geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America held a dominant market share of 35% in the year 2021. An increase in healthcare infrastructure, high expenditure on health, and continuous prevalence of enterovirus in North America drive the market. As per the enterovirus-foundation organization, In the United States, about 30 to 50 million annual infections result in approximately 10 to 15 million symptomatic cases, with coxsackievirus A6, echovirus 11, echovirus 18, coxsackievirus A9, coxsackievirus B4, echovirus 30, echovirus 6, and enterovirus D69 accounting for approximately 50% of enteroviral infections. More than 80% of infections occur in people under the age of 20, with the highest rates occurring in newborns and children aged 4 and under. Infants under the age of 1 year account for about half of all infections. As the nature of enterovirus is asymptomatic and hard to detect on time, a threat to children and adolescents needs good diagnostics measures which fuel the growth of Enterovirus Diagnostics Market Size.
Furthermore, Europe is estimated to grow with the fastest CAGR rate of 9.0% over the forecast period 2022-2027. Europe is a developed region with the best healthcare and infrastructure facility, but the prevalence of enterovirus is very high. Worldwide, an estimated 1 billion or more enteroviral infections occur annually. After releasing lockdown in Europe, outbreak of enterovirus D68 (EV-D68) is identified between July 31 to 14 October 2021 reported by euro surveillance. In this current outbreak, the most highlighted thing to concern is that 55% of infected people are from the 2- 5 years of age group. Such continuous outbreaks of enterovirus in Europe fuel the Enterovirus Diagnostic Market Size over the forecast period 2022-2027.
Enterovirus Diagnostics Market Drivers
Increase in Respiratory Disease Drive Market.
With the increase in respiratory tract infections around the world, there is an emerging need for enterovirus diagnostic. India which ranks number two in population and with 18% of the global population reported 41,996,260 cases and 3,740 deaths from respiratory infection, as per a 2019 report published in the National Health Portal of India. The major market players with advanced technology for enterovirus diagnostic kits, advancements in technology such as home delivery of such kits for self-testing enterovirus infection is driving the Enterovirus Diagnostics Industry.
Advanced Technology for Enterovirus Testing Aid Market Growth.
Diagnosis of Enterovirus is very difficult without the use of advanced technology, as it shows atypical symptoms. To detect the disease advanced level techniques such as PCR, ELISA, and enzymatic methods are used. In clinical laboratories and diagnostic centers, PCR is used attributed to the high sensitivity of PCR enterovirus identification is 96%, with 86% and 99% positive and negative predictive values, respectively with a 96% accuracy rate in diagnosing Enterovirus detection status. Geneproof, Biomerieux, and Altona diagnostics are some companies providing PCR test kits for enterovirus detection. Such advanced technology for enterovirus diagnostics fuels the growth of the Enterovirus Diagnostics Industry.
Enterovirus Diagnostics Market Challenges
The Expansion of the Market is being Hampered by Difficulties in the Diagnosis of Viral Encephalitis in Children
According to NCBI, there is evidence that several enteroviruses can affect the central nervous system and result in a range of neurological symptoms, including encephalitis, meningitis, paralysis, and ataxia. As it can cause poliomyelitis in newborns and young children, poliovirus is the most well-known among these pathogens. According to Infectious Diseases Reports by MDPI, the majority of enteroviral encephalitis diagnoses are based on CSF PCR results that are positive, with a reported sensitivity of between 75% and 95%. Enteroviruses, on the other hand, are RNA viruses, which means that the genetic stability of the viral RNA decreases over time and that the sensitivity of the EV CSF PCR is low when CSF samples are not taken early, i.e., in the first 3 days of the sickness. The accurate application of proper transport techniques (70 C) or when the viral load in the CSF is below the PCR assay's limit of detection undermines the ability to detect enteroviral RNA which is posing challenges in the diagnosis of the virus. In the research, CSF samples were appropriately transferred and preserved, and an enteroviral reference lab utilized a highly sensitive and exact PCR technique. However, the late timing of the CSF sample collection—on the sixth day of fever—has had an adverse impact on the PCR CSF results which is hampering the Enterovirus Diagnostics Industry growth.
Enterovirus Diagnostics Industry Outlook:
Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Enterovirus Diagnostics Market. The top 10 companies in the Enterovirus Diagnostics Market companies are:
- Beckman Coulter/Danaher
- Becton Dickinson
- Eiken Chemical
- In March 2022, Beckman Coulter launched CellMekSPS – a fully automated sample preparation system for clinical flow cytometry lab which enables lean workflow and helps to grow lab efficiency by streaming and automating manual preparation. It can hold up to 53 vials with the option to run a third-party reagent.
- In July 2020, Becton Dickinson – a leading global medical technology company, announced the formation of a strategic, public-private partnership with the Biomedical Advanced Research and Development Authority (BARDA), to develop new manufacturing lines for injection devices with priority access to the U.S government. BARDA is estimated to invest $42 million investment in this project.
- In November 2020, bioMerieux – a world leader in the field of in vitro diagnostic announced the expansion of its ARSENE range for detection of SARS – CoV – 2. This test includes the use of three samples nasopharyngeal swab, oropharyngeal swab, and saliva with a real-time PCR test.
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