Transfection Technologies Market - Forecast(2023 - 2028)
Transfection Technologies Market Overview
Transfection Technologies Market size is estimated to reach $1.7 billion by 2027, growing at a CAGR of 8.1% during the forecast period 2022-2027. Transfection can be delineated as a method taken into consideration to introduce naturally occurring chemical compounds that are nucleic acids into cells. Nucleic acids such as deoxyribonucleic acid and ribonucleic acid are considered to alter the genetic content of host cells. It isn’t a piece of cake to penetrate a cell and introduce foreign nucleic acids as the cellular membrane shields them from the outer environment. Therefore, several microbiology techniques like electroporation and magnet assisted transfection is used to broaden the porousness of the cell membrane so that chemicals or DNA can be introduced without any hindrance. The transfection technologies market outlook is exceptionally bewitching as they have a wide range of applications in coming across detailed biomarkers by getting the hang of molecular pathway of maladies and these biomarkers can be useful in the diagnosis of ailments like cancer. Far-reaching applications in protein production and vaccine development, proliferation in the prevalence of cancer and other chronic illnesses as the geriatric population is on a precipitous upsurge are the most prominent factors set to drive the growth of the Transfection Technologies Market for the period 2022-2027.
The report: “Transfection Technologies Market Forecast (2022-2027)”, by Industry ARC, covers an in-depth analysis of the following segments of the Transfection Technologies Market.
Research (cancer research, biomedical research), Therapeutics, Protein
production and studies, and others.
By Method Type: Biological methods (virus-mediated transfection or transduction), Chemical based transfection (magnetic beads, Cationic amino acids and polymers, lipofection, cationic lipids, calcium phosphate, and others), Instrument based method (Biolistic particle delivery, laserfection, electroporation, direct microinjection, and others).
By Technology: Biochemical, Physical, and Viral-Vector based Transfection.
By End User: Hospitals, Research laboratories, Pharma and Biopharmaceutical firms, Academic institutions.
By Geography: North America (U.S., Canada, and Mexico), Europe (Germany, UK, France, Italy, Spain, Russia, and Rest of Europe), Asia-Pacific (China, India, Japan, South Korea, Australia & New Zealand, and Rest of Asia-Pacific), South America (Brazil, Argentina, Chile, Colombia and Rest of South America) and Rest of World (the Middle East and Africa).
- Geographically, the North America Transfection Technologies Market accounted for the highest revenue share in 2021. However, Asia-pacific is poised to dominate the market over the period 2022-2027.
- Heightening research and development activities associated with novel discoveries of drugs and transfection techniques and enlarging demand for precise therapeutic procedures are said to be preeminent drivers driving the growth of the Transfection Technologies Market. Moreover, the grim requirement of innumerable hard cash and cell damage incidences due to transfection are said to reduce the market growth.
- Detailed analysis of the Strength, Weaknesses, and Opportunities of the prominent players operating in the market will be provided in the Transfection Technologies Market report.
Transfection Technologies Market Share, By Geography (%) in 2021
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Transfection Technologies Market Segment Analysis-By Technology Type
The Transfection Technologies Market based on the technology type can be further segmented into biological methods (virus-mediated transfection or transduction), chemical-based transfection (magnetic beads, cationic amino acids and polymers, lipofection, cationic lipids, calcium phosphate, and others), Instrument based method (Biolistic particle delivery, laserfection, electroporation, direct microinjection, and others). The biological and chemical-based method segment held the largest share in 2021. The growth is owing to the high preciseness of the viral vector as compared to gene transduction as virus-mediated transfection makes use of a viral vector to deliver DNA and RNA into the cells. Biological methods are used frequently owing to their meticulousness in gene delivery. Moreover, viral vector in transduction extends the advantages of easy permeability in cells that are quite rigid to bisect making it easy to accomplish transgene countenance in vivo. On another hand, chemical-based methods are very cost-effective and easy to use making them the first choice of many researchers. However, the Instrument-based segment is estimated to be the fastest-growing segment with a CAGR of 9.8% over the forecast period 2022-2027. This growth is owing to their flexibility and ease of working with a diversity of cells. Moreover, these methods are quite well-organized therefore can be operated in alive organisms.
Transfection Technologies Market Segment Analysis-By End User
The Transfection Technologies Market based on end-user can be further segmented into Hospitals, Research laboratories, Pharma and Biopharmaceutical firms, and Academic institutions. The pharmaceutical and biopharmaceutical along segment held the largest share in 2021. The growth is owing to round-the-clock research activities in an attempt to develop an effective cure for COVID-19 vaccines. The demand for acetaminophen and ivermectin as corona cases are spiking ensuring billions of dollars to pharmaceutical companies. As a result, companies have heightened their quest for vaccine developments where transfection technologies play a crucial role. Moreover, this same segment is estimated to be the fastest-growing segment with a CAGR of 9.3% over the forecast period 2022-2027. This growth is owing to the ineffectiveness of vaccines against mutated variants of the COVID-19. The pharma and biopharma companies are slogging through too much as the prevalence of cancer is expected to reach epidemic proportions in foreseeable future.
Transfection Technologies Market Segment Analysis-By Geography
The Transfection Technologies Market based on Geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America held the largest share with 38% of the overall market in 2021. The growth in this segment is owing to the factors such as the presence of state-of-the-art research laboratories and top-flight pharmaceutical players that are assisting in research and development at a relentless pace. The full-fledged economies of North American states subject them to spending an incalculable amount of riches to develop contemporary cures. Moreover, plunging incidences of obesity and breast cancer among people in the US is another big factor in the dominance of this segment in the transfection technologies market. Nevertheless, the Asia-pacific segment is expected to be the fastest-growing segment over the forecast period 2022-2027. This growth is owing to heightened incidences of infections attributed to poor intake and bizarre eating habits, especially in nations like China, Thailand, and India. On another hand, due to the upsurging old-age population cardiovascular illnesses are griping this continent. Nevertheless, the rising wealth of countries is encouraging them to refine their existing healthcare infrastructure and research proficiencies.
Transfection Technologies Market Drivers
Expanding incidences of chronic illnesses are Anticipated to Boost Product Demand
The accruing chronic maladies and viral infections are the primary reason behind broadening mortality rates and the number of hospitalizations around the globe. With declining, immunities people are turning more prone to such illnesses. As of 2021, more than 14% of an adult residing in the U.S. were reported with more than 1 chronic ailment. In addition to that, 43-44% of millennials who are in their early 40s are afflicted with some sort of chronic condition. Besides, around 1.9 million cases of cancer were found worldwide which eventually led to more than 600,000 fatalities in 2021. Moreover, over 130,000 deaths are being reported every year in the US due to lung cancer. Considering these trends, the demand for transfection technologies has heightened in recent years.
Heightened flows of riches in research and development as communicable viruses are griping the world are Expected to Boost Product Demand
The private players in the market have increased their efforts to overcome the drawbacks of existing transfection technologies. For instance, Thermo Fisher scientific a major player in the transfection technologies market increase its research spending by more than $150 million in 2020 when it allocated around $1,181 million to research and development. The numbers are bound to rise with the rising profit of pharmaceutical companies due to the pandemic and are anticipated to drive the market forward.
Transfection Technologies Market Challenges
The exorbitant cost of instruments and drawback of transfection methods is Anticipated to Hamper Market Growth
The instruments required to perform the transfection process are expensive which can be a challenge for the market. Even though chemical transfection methods are slightly cost-effective but they are prone to errors also. Moreover, the usage of chemicals like calcium phosphate can affect cell functioning adversely. The total DNA amount used in calcium phosphate transfection is usually 10–50 ?g in 450 ?L sterile water and 50 ?L of 2.5 M CaCl2 per 10-cm dish but varies widely among plasmid preparations as well as with different cells and media. Methods like electroporation and microinjections are considered harmful as they can mutilate the cells during the penetration of the cellular membrane due to larger pores and ion imbalance which is anticipated to cripple the growth of the transfection technologies market.
Transfection Technologies Industry Outlook:
Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Transfection Technologies Market. Key companies in this market are-
- Lonza Group
- Sigma Aldrich
- Thermo Fisher
- Bio-Rad Laboratories Inc.
- Life technologies
- Roche Holding AG
- Promega Corporation
- SignaGen Laboratories
- On February 3, 2022, Polypus, a provider of transfection reagents acquired e-Zyvec, a France-based provider of DNA design and production services for custom-made DNA vectors to expand their expertise in the plasmid DNA vector engineering.
- On April 15, 2021, US-based company “Thermo Fisher Scientific” which is famous for its reagent and other instrument supplies concluded the acquisition of US-based CRO “Pharmaceutical Product Development.” A payment of $17.4 billion was made to PPD. The acquisition strengthens the clinical research portfolio of Thermo Fisher.
- On April 9, 2020, California, United States-based company “Bio-Rad Laboratories” which develops special technology for life science successfully acquired the company “Celsee.” Celsee is a US-based firm that deals in transfection technologies. The financials of the deal weren’t publicized but Bio-Rad claimed that the transaction will help the company in the expertise of single-cell analysis.
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