The Superdisintegrants Market size is estimated to reach $571.7 million by 2027, growing at a CAGR of 7.7% during the forecast period 2022-2027. The growth of the Superdisintegrants Market is greatly fueled by the growing acceptance of orally disintegrating tablets and the rising count of pediatric patients and the geriatric population. Superdisintegrants constitute the category of compounds that fundamentally assist the brisk disintegration of orally disintegrating tablets in the oral cavity. The orally disintegrating tablet is a solid dosage arrangement that expeditiously disintegrates or mixes in the mouth within one minute and does not need water for swallowing. The demand for speedy disintegrating tablets and capsules has been rising specifically for geriatric and pediatric patients due to swallowing hardships. Presently, numerous more novel agents have been greatly developed and recognized as Superdisintegrants. Synthetic Superdistintegrants include modified starch, modified cellulose and crospovidone. 

Superdisintegrants Market Growth Drivers:

Surging Applications of Synthetic Superdisintegrants:

A class of Superdisintegrants involving Croscarmellose sodium (Ac-Di-Sol), sodium starch glycolate (Primogel, Explotab) and crospovidone (Polyplasdone XL) relieve most of the issues. Sodium starch glycolate is a modified potato starch excipient. Investigations have been conducted involving modified starches where cross-linked sodium carboxymethylated pea starch (SCPS) was synthesized and assessed as tablet superdisintegrant in diclofenac sodium-based tablets. Sodium starch glycolate is a typically applied superdisintegrant, engaged to advance accelerated disintegration and dissolution of IR dosage forms. Cross-linked sodium carboxymethyl cellulose is also termed croscarmellose sodium or modified cellulose gum. Modified cellulose gum is applied as a superdisintegrant in pharmaceutical formulations. Typically, crospovidone is utilized at a concentration of 2%–5% w/w (Rowe et al., 2009). Crospovidone wicks saliva into the tablet fast to produce the volume expansion and hydrostatic pressures essential to support breakneck disintegration in the mouth. The surging applications of Synthetic Superdisintegrants are therefore driving the growth of the Superdisintegrants Industry, thereby contributing to the Superdisintegrants Industry Outlook.

Soaring Applications of Mouth-dissolving Tablets:

Mouth-dissolving tablets are specifically advantageous for pediatric and geriatric patients. It is supposed that 50% of the population is influenced by dysphagia or difficulty in swallowing, which leads to a great incidence of non-compliance and inefficient therapy. Mouth dissolving tablets (MDT) disintegrate instantly when established on the tongue, discharging the medication that dissolves or distributes in the saliva. In MDT, superdisintegrants are included in the correct quantity for fast disintegration with enhanced bioavailability. On the basis of the source, different kinds of superdisintegrants are available. They are synthetic, semi-synthetic, natural and co-processed. The soaring applications of mouth-dissolving tablets are therefore propelling the growth of the Superdisintegrants Market.

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In May 2021, DuPont Mobility & Materials declared that it was granting $5 million in capital and operating resources at its manufacturing facilities in Germany and Switzerland. This was performed to boost capacity for its high-performance automotive adhesives.

Superdisintegrants Market: Competitive Landscape

Key companies holding major shares in the Superdisintegrants Market are BASF SE, Ashland Global Holdings Inc., DuPont, Roquette Freres, DFE Pharma, JRS Pharma, Asahi Kasei Corporation, Merck KGaA, Corel Pharma Chem and FMC Corporation.

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