Viral Inactivation Market - Forecast(2024 - 2030)

Viral Inactivation Market Overview

Viral Inactivation Market size is estimated to reach $1.06 billion by 2027, growing at a CAGR of 12.3% during the forecast period 2022-2027. Viral inactivation is performed at all levels of the pharmaceutical and biopharmaceutical production technique to reduce the hazard of product infection. Viral inactivation is to halt the viruses in a given sample from infecting the chosen product either by eliminating viruses entirely or rendering them non-infectious. These procedures are utilized extensively in the food and blood plasma industries, as those products can be damaged by the existence of viral particles. Animal parvoviruses have classically been bestowed the status of “highly resistant to inactivation”. This status has been based chiefly on the well-recognized heat and chemical inactivation resistance of the animal parvoviruses (particularly porcine, canine, bovine, and murine parvoviruses) in liquid inactivation settings. Purification techniques are planned to offer different, orthogonal procedures of virus elimination or inactivation, inclusive of chromatography, nanofiltration, solvent–detergent treatment, low pH inactivation, or heat treatment. Acidic pH inactivation is generally utilized to inactivate viruses.

The increasing endorsements of novel medications and rules related to viral security of biologics are set to drive the Viral Inactivation Market. The expansion of the biologics and biosimilars industry applying different viral inactivation techniques like acidic pH inactivation is set to propel the growth of the Viral Inactivation Market during the forecast period 2022-2027. This represents the Viral Inactivation Industry Outlook. 

Report Coverage

The report: “Viral Inactivation Market Forecast (2022-2027)”, by Industry ARC, covers an in-depth analysis of the following segments of the Viral Inactivation Market.

By Product: Viral Inactivation System And Accessories, Kits And Reagents, Others.
By Method: Solvent Detergent Method, pH Adjustment Method, Pasteurization, Others.
By Application: Vaccines And Therapeutics, Blood And Blood Products, Cellular And Gene Therapy Products, Others.
By End User: Pharmaceutical and Biotechnology Companies, Contract Research Organizations, Others.
By Geography: North America (the U.S, Canada, and Mexico), Europe (UK, Germany, France, Italy, Spain, Russia and Rest of Europe), Asia-Pacific (China, India, Japan, South Korea, Australia & New Zealand, and Rest of Asia-Pacific), South America (Brazil, Argentina, Rest of South America) and Rest Of The World (Middle East, Africa).

Key Takeaways

• Geographically, North America Viral Inactivation Market accounted for the highest revenue share in 2021 and it is poised to dominate the market over the period 2022-2027 owing to the presence of progressive healthcare infrastructure and the existence of preeminent pharmaceutical and biopharmaceutical firms employing viral inactivation procedures like acidic pH inactivation in the North American region.

• Viral Inactivation Market growth is being driven by the increasing predominance of incessant ailments like cancer and autoimmune ailments resulting in greater utilization of viral inactivation techniques like acidic pH inactivation. However, the great magnitude of market consolidation is one of the major factors hampering the growth of the Viral Inactivation Market.

• Viral Inactivation Market Detailed Analysis on the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Viral Inactivation Market report. 

The Viral Inactivation Market based on the product can be further segmented into Viral Inactivation System And Accessories, Kits And Reagents and Others. The Kits And Reagents Segment held the largest market share in 2021. This growth is owing to the continued application by pharmaceutical and biopharmaceutical firms. The boost in the count of pharmaceutical and biopharmaceutical firms employing acidic pH inactivation, the extensive application in different end use environments and an increase in R&D expenditure for novel drug development are further propelling the growth of the kits and reagents segment.

Furthermore, the Others segment is estimated to grow with the fastest CAGR of 13.2% during the forecast period 2022-2027 owing to the effortless management and specially-designed services provided by service offering firms together with increased utilization of viral inactivation techniques like acidic pH inactivation.

Viral Inactivation Market Segment Analysis – By Application:

The Viral Inactivation Market based on application can be further segmented into Vaccines And Therapeutics, Blood And Blood Products, Cellular And Gene Therapy Products and Others. The Vaccines And Therapeutics Segment held the largest market share in 2021. This growth is owing to the increasing predominance and enormous economic burden of incessant ailments like Cancer, that need inactivated vaccines in conjunction with heightening government backing for pharmaceutical and biotechnology industries to invest in R&D of new therapeutics. Chromatography and acidic pH inactivation is generally utilized for viral inactivation. The increasing prominence given to viral inactivation by making it compulsory by regulatory authorities like the US Food and Drug Association (FDA) for investigational new drug (IND) submission in view of security issues is further propelling the growth of the viral inactivation market.

Furthermore, the Others segment is estimated to grow with the fastest CAGR of 13.4% during the forecast period 2022-2027 owing to the soaring research and development efforts in stem cell research in developed economies like U.S. and European countries in conjunction with the increased application of viral inactivation techniques like acidic pH inactivation.

Viral Inactivation Market Segment Analysis – By Geography:

The Viral Inactivation Market based on geography can be further segmented into North America, Europe, Asia-Pacific, South America and Rest of the World. North America (Viral Inactivation Market) held the largest share with 34% of the overall market in 2021. The growth of this region is owing to the soaring concentration of key players like Texcell in the region. The considerable spend on healthcare R&D by government and firms in the U.S. in conjunction with increased application of viral inactivation techniques like acidic pH inactivation are further propelling the growth of the Viral Inactivation Market in the North American region.

Furthermore, the Asia-Pacific region is estimated to be the region with the fastest CAGR rate over the forecast period 2022-2027. This growth is owing to factors like growing healthcare infrastructure in developing economies and increasing awareness initiatives about viral inactivation techniques like acidic pH inactivation. The continuing trials and increasing predominance of incessant ailments in countries like India and China is fuelling the progress of the Viral Inactivation Market in the Asia-Pacific region.

Viral Inactivation Market - Drivers

Recognition Of Possible Novel Treatment For COVID-19 Is Projected To Drive The Growth Of Viral Inactivation Market:

In October 2021, researchers at the time of a current investigation recognized a possible novel treatment that restrains the replication of SARS-CoV-2, the virus that brings about Covid-19. Viral inactivation techniques include acidic pH inactivation and chromatography. To reproduce, all viruses, inclusive of coronaviruses, contaminate cells and reprogramme them to generate novel viruses. The study 'Targeting the pentose phosphate pathway for SARS-CoV-2 therapy' has been printed by the scientific journal Metabolite. The research disclosed that cells contaminated with SARS-CoV-2 can only generate novel coronaviruses when their metabolic pentose phosphate pathway is stimulated. When utilizing the drug benfooxythiamine, an inhibitor of this pathway, SARS-CoV-2 replication was restrained and contaminated cells did not generate coronaviruses. The research from the University of Kent's School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, discovered that the drug also raised the antiviral activity of '2-deoxy-D-glucose'; a drug which alters the host cell's metabolism to minimize virus multiplication. This demonstrates that pentose phosphate pathway inhibitors like benfooxythiamine are a probable novel treatment option for COVID-19, both on their own and in integration with added treatments. These kinds of novel research endeavors are fuelling the growth of the Viral Inactivation Market during the forecast period 2022-2027.

Technological Innovations Are Expected To Boost The Demand Of The Viral Inactivation Market:

Technological innovations are driving the growth of the Viral Inactivation market. Acidic pH Inactivation is a typical viral inactivation technique. Flexact® for low pH virus inactivation, developed by Sartorius, is completely scalable from 50L to 2,000L. The Flexact® controller is interchangeable all through the different steps of the technique. This flexibility makes it perfect for utilization in multi-product facilities offering versatility and cost minimization owing to the non-requirement of a segregated unit for every process step. With the combined single-use pH sensor and rare automated pH adjustment Flexact® Modular allows accurate and quick virus clearance step in the mAb technique. The core of Flexact® Modular, the controller, has been planned to be utilized in any application. This means that Flexact® Modular can be reconfigured in simply a few effortless steps. These kinds of technological innovations are driving the growth of the Viral Inactivation Market during the forecast period 2022-2027.

Viral Inactivation Market – Challenges

Limitations Imposed By Biosimilars Are Challenging The Growth Of The Viral Inactivation Market:

The manufacturing technique of biosimilars is expensive, making it a demanding sector for the entry of novel entrants. Viral infection is a typical threat to all animal- and human-derived biopharmaceuticals. This kind of infection can influence any portion of a bioproduction process, Therefore biomanufacturers require to carry out viral testing investigations and include viral clearance techniques into their procedures. Pharmaceutical firms developing biosimilars and biobetters need to confirm that the efficacy, security, and purity of their products are similar to those of original innovator-approved drugs. In this technique, viral security is vital. The sourcing of raw materials is one of the biggest issues for regulators and biopharmaceutical producers. Nearly all occurrences of viral infection result from utilizing poorly characterized materials. This hazard is magnified by the sourcing of raw materials from different vendors. Viral infection is not essentially a rare happening owing to big volumes of process media and gases being utilized to manufacture biologics. These issues are making viral clearance vital and making viral inactivation challenging and hamper the growth of the Viral Inactivation Market.

Viral Inactivation Market - Landscape:

Product launches, mergers & acquisitions, joint ventures and R&D activities are key strategies adopted by players in the Viral Inactivation Market. Key companies of this market include:

1. Merck KGaA
2. Sartorius
3. Texcell
4. Cytiva
5. Parker Hannifin
6. Danaher
7. Rad Source Technologies
8. SGS S.A.
9. Clean Cells Inc.
10. Charles River Laboratories

Acquisitions/Product Launches:

• In March 2021, Charles River Laboratories International, Inc. declared that it has acquired Retrogenix Limited, an early-phase contract research organization (CRO) offering specially-designed bioanalytical services using its proprietary cell microarray technology.

• In July 2021, SGS declared the introduction of novel mobile units for transporting in-situ Electromagnetic Compatibility (EMC) and Electromagnetic Interference (EMI) testing services to sites across the U.S.

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