Transfection Reagents & Equipment Market - Forecast(2024 - 2030)

Report Code: HCR 0482 Report Format: PDF + Excel

Transfection Reagents & Equipment Market Overview

The Transfection Reagents & Equipment market size is estimated to reach $1.4 billion by 2026, growing at a CAGR of 7.5% during the forecast period 2021-2026. Transfection is the process by which naked or purified nucleic acids are purposefully introduced into eukaryotic cells. Transfection reagents use physical or chemical means to deliver the nucleic acid into the cells. Some of the common methods used for transfection include Biochemical, Calcium Phosphate, Nucleofection, and Electroporation. These methods are used for multiple applications such as synthetic gene therapy and gene expression studies, protein therapeutics and production, and cancer research. The rapid growth in technological advancements in this field is anticipated to drive the market during the forecast period. However, the high cost of transfection reagents acts as a key challenge for the Transfection Reagents & Equipment Industry.

Report Coverage

The report: “Transfection Reagents & Equipment Market Forecast (2021-2026)”, by Industry ARC, covers an in-depth analysis of the following segments of the Transfection Reagents & Equipment Market.

By Product Type: Reagents and Equipment.
By Method: Electroporation, Liposomes, Particle Bombardment, Microinjection, Adenoviral Vectors, Calcium Phosphate, DEAE-dextran, Magnetic Beads, Activated Dendrimers, and Laserfection.
By Application: Gene Expression Studies, Protein Production, Transgenic Models, Therapeutic Delivery, Cancer Research, and Biomedical Research.
By End User: Pharmaceutical & Biotechnology Companies, and Academics & Research Institutes.
By Geography: North America (U.S., Canada, and Mexico), Europe (Germany, UK, France, Italy, Spain, Russia, and Rest of Europe), Asia-Pacific (China, India, Japan, South Korea, Australia & New Zealand, and Rest of Asia-Pacific), South America (Brazil, Argentina, and Rest of South America) and Rest of World (the Middle East and Africa).

Key Takeaways

  • Geographically, North America accounted for the largest Transfection Reagents & Equipment market share in 2020 owing to the favorable reimbursement policies and availability of advanced technologies in the region.
  • An increase in the prevalence of cancer is driving the market for Transfection Reagents & Equipment during the forecast period. However, the lack of skilled professionals in low and middle-income countries is a major challenge for demand generation.
  • Detailed analysis on the Strength, Weaknesses, and Opportunities of the prominent players operating in the market will be provided in the Transfection Reagents & Equipment Market Report. 

    Transfection Reagents & Equipment Market Share, By Method, 2020(%)
Transfection Reagents & Equipment Market
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Transfection Reagents & Equipment Market Segment Analysis - By Product Type

Based on Product Type, the Transfection Reagents & Equipment Market is segmented into Reagents and Equipment. The Reagent segment is anticipated to have the largest share of the market in 2020 and is also projected to have the fastest growth at a CAGR of 7.9% during the forecast period 2021-2026. This is attributed to the routine use of transfection reagents for various experiments related to gene research and protein production. Moreover, the increase in the frequency of innovative reagent launches by major industry players is also contributing to the growth of this segment. In chemical transfection, the reagent combines with the nucleic acid to form positively charged complexes. This charge helps them bind to the surface of the cells. Once inside the cell, the reagents also help destabilize the cell’s endosomal membrane.

Transfection Reagents & Equipment Market Segment Analysis - By Method

The Transfection Reagents & Equipment Market based on Method can be further segmented into Electroporation, Liposomes, Particle Bombardment, Microinjection, Adenoviral Vectors, Calcium Phosphate, DEAE-dextran, Magnetic Beads, Activated Dendrimers, and Laserfection. The Calcium Phosphate segment accounted for the largest share of the market in 2020 and is also poised to witness the fastest growth at a CAGR of 8.4% during the forecast period 2021-2026. Calcium phosphate transfection is the most widely used method of introducing foreign DNA plasmids to cells owing to their high-cost efficiency and simplicity. The DNA and calcium phosphate combine and precipitate, which is then internalized by the cells. The Liposomes segment is also projected to witness significant growth during the forecast period owing to their high reproducibility and ability to transfect multiple types of nucleic acids into a wide range of cell types.

Transfection Reagents & Equipment Market Segment Analysis - By Geography

The Transfection Reagents & Equipment Market based on Geography can be segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. The North American segment is projected to dominate the Transfection Reagents & Equipment market during the forecast period 2021-2026 with a market share of 32% owing to the presence of highly developed healthcare infrastructure, favorable reimbursement policies, and increasing prevalence of cancer in the region. Moreover, the presence of key industry players such as Thermo Fisher Scientific, Promega Corporation, Bio-Rad Laboratories, Sigma-Aldrich Corporation, Mirus Bio, and MaxCyte in the region ensures lower costs, higher innovation, and more options for the end-user industries. The Asia Pacific region is predicted to register the fastest growth owing to the rising healthcare expenditure and growing government initiatives in the region.

Transfection Reagents & Equipment Market Drivers

The Increase in Cancer Patients is Projected to Drive Market Growth.

Around 19.3 million new cancer cases occurred globally and almost 10 million people died from cancer-related causes in 2020. Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung (11.4%), colorectal (10.0 %), prostate (7.3%), and stomach (5.6%) cancers. Lung cancer accounted for more than 1.8 million or 18% of all cancer-related deaths in 2020. Moreover, the global cancer burden is projected to increase by 47% to reach 8.4 million by the year 2040. This is driving the market as transfection reagents play a crucial role in cancer research.

Growing Government Healthcare Expenditure is Anticipated to Boost Product Demand.

The US health care spending increased by 4.6% in 2019, reaching $3.8 trillion or $11,582 per person. As a share of the country’s GDP, spending accounted for 17.7%. According to the Centers for Medicare & Medicaid Services (CMS), the US healthcare system spent around $174 billion or 5% of total spending on research and development activities. Moreover, the healthcare industry spent $121.8 billion on R&D by investing in structures and equipment. Furthermore, 51.7% of the total R&D investment went into the biopharmaceutical industry. The high investments in R&D are driving the market for Transfection Reagents & Equipment as they increase the purchasing power of the research facilities.

Transfection Reagents & Equipment Market Challenges

The Lack of Skilled Professionals is Anticipated to Hamper Market Growth.

The lack of skilled professionals necessary for activities such as cancer research, protein production and gene expression studies are challenging the demand generation, especially in low and middle-income regions. For instance, the Philippines has only around 188 researches for every 1 million inhabitants compared to around 7537 per 1 million in a developed country such as Sweden. Meanwhile, other developing regions such as Laos and Cambodia only have 16 and 29 researchers per 1 million population respectively. This leads to the lack of penetration of Transfection Reagents & Equipment in these regions even though their markets have high potential.

Limitations of Transfection Reagents are Projected to Limit Growth Opportunities

The limitations of various transfection reagents are challenging the growth of the market during the forecast period. For instance, Calcium Phosphate reagents have extremely low transfection effectiveness, ranging between only 1% to 10%. This makes it challenging to produce reproducible results. Lipofection techniques can be highly toxic and the cells that survive the transfection procedure suffer from severe morphological changes. Moreover, the Microinjection procedure requires highly expensive equipment and the transfection rate is also low. Furthermore, the prolonged voltage pulse of the Electroporation procedure can be toxic to the cells. These disadvantages along with the expensive equipment necessary for the procedure significantly limit the usage of transfection procedures.

Transfection Reagents & Equipment Market Industry Outlook:

Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Transfection Reagents & Equipment Market. The top 10 companies of the industry include:

  1. Lonza Group
  2. Merck KGaA
  3. Bio-Rad Laboratories, Inc.
  4. Thermo Fisher Scientific Inc.
  5. MaxCyte Inc.
  6. Mirus Bio LLC.
  7. Promega Corporation
  8. Horizon Discovery Ltd.
  9. Polyplus-transfection
  10. F. Hoffmann-La Roche Ltd.

Partnerships/Product Launches:

  • In August 2021, Polypus announced the launch of a transfection reagent for large-scale viral vector production called FectoVIR-AAV GMP. FectoVIR-AAV GMP will help manufacturers alleviate some of the pain points regarding linear process scalability and flexibility.
  • In May 2019, Altogen Biosystems announced the launch of their GMP grade liver targeted transfection reagent for in vivo delivery of biomolecules. The transfection reagent features liposome-based microscopic compounds that are coated with biodegradable polymers and attached to nucleic acids.

Relevant Reports:

Transfection Technologies Market - Forecast (2021 - 2026)
Report Code: HCR 75986

Gene Expression Analysis Market - Forecast (2021 - 2026)
Report Code: HCR 0415

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1. Transfection Reagents & Equipment Market - Overview
    1.1 Definitions and Scope
2. Transfection Reagents & Equipment Market - Executive Summary
    2.1 Market Revenue and Key Trends by Company
    2.2 Key trends by Product Type
    2.3 Key trends by End User
    2.4 Key trends by Geography
3. Transfection Reagents & Equipment Market – Comparative Analysis
    3.1 Company Benchmarking – Key Companies
    3.2 Financial Analysis – Key Companies
    3.3 Market Value Split by Key Companies
    3.4 Patent Analysis
    3.5 Pricing Analysis – Average Selling Price
4. Transfection Reagents & Equipment Market - Startup Companies Scenario Premium
    4.1 Key Startup Company Analysis by
        4.1.1 Investment
        4.1.2 Revenue
        4.1.3 Venture Capital and Funding Scenario
5. Transfection Reagents & Equipment Market – Industry Market Entry Scenario Premium Premium
    5.1 Regulatory Framework Overview
    5.2 New Business and Ease of Doing business index
    5.3 Case Studies of Successful Ventures
6. Transfection Reagents & Equipment Market - Forces
    6.1 Market Drivers
    6.2 Market Constraints/Challenges
    6.3 Porters five force model
        6.3.1 Bargaining power of suppliers
        6.3.2 Bargaining powers of customers
        6.3.3 Threat of new entrants
        6.3.4 Rivalry among existing players
        6.3.5 Threat of substitutes
7. Transfection Reagents & Equipment Market – Strategic Analysis
    7.1 Value Chain Analysis
    7.2 Opportunities Analysis
    7.3 Market Life Cycle
8. Transfection Reagents & Equipment Market – By Product Type (Market Size –$Million/$Billion)
    8.1 Reagents
    8.2 Equipment
9. Transfection Reagents & Equipment Market – By Method (Market Size –$Million/$Billion)
    9.1 Electroporation
    9.2 Liposomes
    9.3 Particle Bombardment
    9.4 Microinjection
    9.5 Adenoviral Vectors
    9.6 Calcium Phosphate
    9.7 DEAE-dextran
    9.8 Magnetic Beads
    9.9 Activated Dendrimers
    9.10 Laserfection
10. Transfection Reagents & Equipment Market – By Application (Market Size –$Million/$Billion)
    10.1 Gene Expression Studies
    10.2 Protein Production
    10.3 Transgenic Models
    10.4 Therapeutic Delivery
    10.5 Cancer Research
    10.6 Biomedical Research
11. Transfection Reagents & Equipment Market - By End User (Market Size –$Million/$Billion)
    11.1 Pharmaceutical & Biotechnology Companies
    11.2 Academics & Research Institutes
12. Transfection Reagents & Equipment Market - By Geography (Market Size –$Million/$Billion)
    12.1 North America
        12.1.1 U.S.
        12.1.2 Mexico
        12.1.3 Canada
    12.2 Europe
        12.2.1 U.K.
        12.2.2 France
        12.2.3 Germany
        12.2.4 Italy
        12.2.5 Spain
        12.2.6 Russia
        12.2.7 Rest of Europe
    12.3 Asia Pacific
        12.3.1 China
        12.3.2 India
        12.3.3 Japan
        12.3.4 South Korea
        12.3.5 Australia & New Zealand
        12.3.6 Rest of Asia Pacific
    12.4 South America
        12.4.1 Brazil
        12.4.2 Argentina
        12.4.3 Rest of South America
    12.5 Rest of the World
        12.5.1 Middle East
        12.5.2 Africa
13. Transfection Reagents & Equipment Market - Entropy
14. Transfection Reagents & Equipment Market – Industry/Segment Competition Landscape Premium
    14.1 Market Share Analysis
        14.1.1 Global Market Share – Key Companies
        14.1.2 Market Share by Region – Key companies
        14.1.3 Market Share by Countries – Key Companies
        14.1.4 Competition Matrix
        14.1.5 Best Practices for Companies
15. Transfection Reagents & Equipment Market – Key Company List by Country Premium Premium
16. Transfection Reagents & Equipment Market Company Analysis
    16.1 Company 1
    16.2 Company 2
    16.3 Company 3
    16.4 Company 4
    16.5 Company 5
    16.6 Company 6
    16.7 Company 7
    16.8 Company 8
    16.9 Company 9
    16.10 Company 10
"*Financials for private companies would be provided on a best-efforts basis”.