Transfection Reagents and Equipment Market Overview
The report: “Transfection Reagents and Equipment Market Forecast (2021-2026)”, by Industry ARC, covers an in-depth analysis of the following segments of the Transfection Reagents and Equipment Market.
By Product Type: Reagents
By Method: Electroporation, Liposomes, Particle Bombardment, Microinjection, Adenoviral Vectors, Calcium Phosphate, DEAE-dextran, Magnetic Beads, Activated Dendrimers, and Laserfection.
By Application: Gene Expression Studies, Protein Production, Transgenic Models, Therapeutic Delivery, Cancer Research, and Biomedical Research.
By End User: Pharmaceutical & Biotechnology Companies, and Academics & Research Institutes.
By Geography: North America (U.S., Canada, and Mexico), Europe (Germany, UK, France, Italy, Spain, Russia, and Rest of Europe), Asia-Pacific (China, India, Japan, South Korea, Australia & New Zealand, and Rest of Asia-Pacific), South America (Brazil, Argentina, and Rest of South America) and Rest of World (the Middle East and Africa).
- Geographically, North America accounted for the largest Transfection Reagents and Equipment market share in 2020 owing to the favorable reimbursement policies and availability of advanced technologies in the region.
- An increase in the prevalence of cancer is driving the market for Transfection Reagents and Equipment during the forecast period. However, the lack of skilled professionals in low and middle-income countries is a major challenge for demand generation.
- Detailed analysis on the Strength, Weaknesses, and
Opportunities of the prominent players operating in the market will be provided
in the Transfection Reagents and Equipment Market Report. Transfection Reagents and Equipment Market Share, By Method, 2020(%)
Transfection Reagents and Equipment Market Segment Analysis - By Product Type
Transfection Reagents and Equipment Market Segment Analysis - By Method
The Transfection Reagents and Equipment Market based on Method can be further segmented into Electroporation, Liposomes, Particle Bombardment, Microinjection, Adenoviral Vectors, Calcium Phosphate, DEAE-dextran, Magnetic Beads, Activated Dendrimers, and Laserfection. The Calcium Phosphate segment accounted for the largest share of the market in 2020 and is also poised to witness the fastest growth at a CAGR of 8.4% during the forecast period 2021-2026. Calcium phosphate transfection is the most widely used method of introducing foreign DNA plasmids to cells owing to their high-cost efficiency and simplicity. The DNA and calcium phosphate combine and precipitate, which is then internalized by the cells. The Liposomes segment is also projected to witness significant growth during the forecast period owing to their high reproducibility and ability to transfect multiple types of nucleic acids into a wide range of cell types.
Transfection Reagents and Equipment Market Segment Analysis - By Geography
Transfection Reagents and Equipment Market Drivers
The Increase in Cancer Patients is Projected to Drive Market Growth.
Around 19.3 million new cancer cases occurred globally and almost 10 million people died from cancer-related causes in 2020. Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung (11.4%), colorectal (10.0 %), prostate (7.3%), and stomach (5.6%) cancers. Lung cancer accounted for more than 1.8 million or 18% of all cancer-related deaths in 2020. Moreover, the global cancer burden is projected to increase by 47% to reach 8.4 million by the year 2040. This is driving the market as transfection reagents play a crucial role in cancer research.
Growing Government Healthcare Expenditure is Anticipated to Boost Product Demand.
The US health care spending increased by 4.6% in 2019, reaching $3.8 trillion or $11,582 per person. As a share of the country’s GDP, spending accounted for 17.7%. According to the Centers for Medicare & Medicaid Services (CMS), the US healthcare system spent around $174 billion or 5% of total spending on research and development activities. Moreover, the healthcare industry spent $121.8 billion on R&D by investing in structures and equipment. Furthermore, 51.7% of the total R&D investment went into the biopharmaceutical industry. The high investments in R&D are driving the market for Transfection Reagents and Equipment as they increase the purchasing power of the research facilities.
Transfection Reagents and Equipment Market Challenges
The Lack of Skilled Professionals is Anticipated to Hamper Market Growth.
The lack of skilled professionals necessary for activities such as cancer research, protein production and gene expression studies are challenging the demand generation, especially in low and middle-income regions. For instance, the Philippines has only around 188 researches for every 1 million inhabitants compared to around 7537 per 1 million in a developed country such as Sweden. Meanwhile, other developing regions such as Laos and Cambodia only have 16 and 29 researchers per 1 million population respectively. This leads to the lack of penetration of Transfection Reagents and Equipment in these regions even though their markets have high potential.
Limitations of Transfection Reagents are Projected to Limit Growth Opportunities
The limitations of various transfection reagents are challenging the growth of the market during the forecast period. For instance, Calcium Phosphate reagents have extremely low transfection effectiveness, ranging between only 1% to 10%. This makes it challenging to produce reproducible results. Lipofection techniques can be highly toxic and the cells that survive the transfection procedure suffer from severe morphological changes. Moreover, the Microinjection procedure requires highly expensive equipment and the transfection rate is also low. Furthermore, the prolonged voltage pulse of the Electroporation procedure can be toxic to the cells. These disadvantages along with the expensive equipment necessary for the procedure significantly limit the usage of transfection procedures.
Transfection Reagents and Equipment Market Industry Outlook:
Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Transfection Reagents and Equipment Market. The top 10 companies of the industry include:
- Lonza Group
- Merck KGaA
- Bio-Rad Laboratories, Inc.
- Thermo Fisher Scientific Inc.
- MaxCyte Inc.
- Mirus Bio LLC.
- Promega Corporation
- Horizon Discovery Ltd.
- F. Hoffmann-La Roche Ltd.
- In August 2021, Polypus announced the launch of a transfection reagent for large-scale viral vector production called FectoVIR-AAV GMP. FectoVIR-AAV GMP will help manufacturers alleviate some of the pain points regarding linear process scalability and flexibility.
- In May 2019, Altogen Biosystems announced the launch of their GMP grade liver targeted transfection reagent for in vivo delivery of biomolecules. The transfection reagent features liposome-based microscopic compounds that are coated with biodegradable polymers and attached to nucleic acids.
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