Hemodialysis Catheter Market - Forecast(2021 - 2026)

Report Code: HCR 86343 Report Format: PDF + Excel (Delivery in 48 Hrs)
Hemodialysis Catheter Market Overview
Hemodialysis Catheter Market size is forecast to reach $1.67 billion by 2025, growing at a CAGR of 5.2% during the forecast period 2020-2025. Hemodialysis is a treatment to filter wastes and water from the blood, as the kidneys do when they were healthy. Hemodialysis helps control blood pressure and balance important minerals, such as potassium, sodium, and calcium, in the blood. The catheter used for hemodialysis is a tunneled catheter as it is placed under the skin. There are two types of tunneled catheters: cuffed or non-cuffed. Non-cuffed tunneled catheters are used for emergencies and for short periods (up to 3 weeks). Tunneled cuffed catheters is a type recommended by the NKF for temporary access. Growing prevalence of chronic kidney diseases owing to unhealthy lifestyle, increasing cases of fatalities owing to kidney problems and various technological innovations for the market products are driving the market growth in recent years. In addition, major developments of key players like Fresenius Medical Care (strategic collaboration) are other factors driving the growth of the market. 

Report Coverage
The report: “Hemodialysis Catheter Market Forecast (2020-2025)”, by IndustryARC, covers an in-depth analysis of the following segments of the Hemodialysis Catheter Market. 

By Product Type:  Cuffed Tunneled Catheter, Non-Cuffed Tunneled Catheter, Non-Tunneled Catheter
By Tip Configuration: Step-Tip Catheter, Split-Tip Catheter, Symmetric Catheter
By Material: Silicone, Polyurethane
By End User: Hospital, Clinics/Dialysis Center, Home Dialysis
By Geography: North America, Europe, Asia-Pacific, Rest of the World (RoW)

Key Takeaways
  • North America dominated the Hemodialysis Catheter Market in the year 2019 owing to the presence of well-developed healthcare system, growing incidences of chronic kidney diseases among the geriatric population and proactive government initiatives to expedite the research activities related to Hemodialysis Catheter. The Hemodialysis Catheter Market scope for different regions will be provided in the final report.
  • Rising kidney disorders among the aged population, increasing incidences of end stage renal diseases (ESRD) and lesser availability of kidney donors for transplantation have helped in significant growth of Hemodialysis Catheter Market. Rising geriatric population and development of intensive-care and portable Hemodialysis Catheter in upcoming years is estimated to drive the industry growth during the forecast period 2020-2025.
  • Detailed analysis on the Strength, Weakness and Opportunities of the prominent players operating in the market will be provided in the Hemodialysis Catheter Market report.
  • Long term risks and side effects of hemodialysis is anticipated to hamper the market growth of the Hemodialysis Catheter Industry.

Product Type - Segment Analysis
Cuffed Tunneled Catheters held the largest share in the product type segment of Hemodialysis Catheter Market in 2019 and is estimated to grow at a CAGR of 4.92% during the forecast period 2020-2025. Cuffed tunneled hemodialysis catheters have a number of advantages over non-cuffed non-tunneled catheters. Adoption of tunneled catchers has helped increase the demand of this segment. Modern cuffed tunneled catheters are made of silicone or polyurethane. Silicone is thermoset and thus the catheter is soft, whilst polyurethane is thermoplastic and softens at body temperature. This reduces endothelial damage and thrombogenicity. Incorporation of the cuff into surrounding tissue and the formation of a subcutaneous tunnel are thought to provide physical barriers to infection. Non-Cuffed Tunneled Catheters held the second largest share, owing to better stiffness than cuffed catheters and thus ideally selected as per vein to be cannulated, in addition to length of time they are left in a particular vein. Cuffed Tunneled Catheters is set to be the fastest growing segment and is estimated to register the highest CAGR during the forecast period 2020-2025, owing to major investments in technology and innovation for its products by key market players.

Material - Segment Analysis
Silicone segment holds the major share in the material segment of Hemodialysis Catheter Market in 2019. Silicone-based catheters are being used with a variety of antibiotic ointments. Both topical and intraluminal antibiotics reduce the rate of bacteremia as well as the need for catheter removal secondary to complications. Owing to the flexibility of these silicone temporary catheters they are inserted using a disposable trocar or a peel-away sheath substituting complexity for an increase in blood flow. Polyurethane segment is forecast to grow at the fastest rate with the highest CAGR during the forecast period 2020-2025, owing to their growing market demand for various advantages over silicone. Polyurethane has a higher tensile strength than silicone, hence it allows catheters to be constructed with a higher inner lumen to outer diameter size ratio and, consequently, higher flow rates in polyurethane catheters versus silicone catheters with the same outer diameter.

Geography - Segment Analysis
North America dominated the geography segment of Hemodialysis Catheter Market with a share of more than 41.6% in 2019, followed by Europe. Growing adoption of renal replacement therapies and increasing incidences of acute kidney injury and chronic kidney diseases has fuelled the market growth in this region. Presence of well-developed healthcare infrastructure, increasing renal care centers and presence of key market players in this region have further helped in the growth of Hemodialysis Catheter Market infrastructure. Europe held the second place in the geography segment share of the market, owing to increasing health awareness and technical advancements in renal replacement therapies.
However, Asia-Pacific is estimated to grow at a higher CAGR during the forecast period 2020-2025. This is owing to growth of healthcare sector in developing countries such as India and China, increasing cases of renal failure among the middle aged population and increasing government aids for technological development of hemodialysis catheters.

Drivers – Hemodialysis Catheter Market

  • Growing prevalence of chronic kidney disorders
The overall prevalence of Chronic Kidney Disorders (CKD) in the general population is approximately 14 percent. High blood pressure and diabetes are the main causes of CKD. Almost half of individuals with CKD also have diabetes and/or self-reported cardiovascular disease (CVD). More than 661,000 Americans have kidney failure. The adjusted CKD stages 1–5 prevalence varied between 3.31% (95% confidence interval [95% CI], 3.30% to 3.33%) in Norway and 17.3% (95% CI, 16.5% to 18.1%) in northeast Germany. In view of rising prevalence of kidney disorders in these regions, the Hemodialysis Catheter Market is set to increase in the forecast period 2020-2025.

  • Lesser availability of kidney donors for transplantation
A systematic review and meta-analysis of observational studies estimating CKD prevalence in general populations worldwide found a consistent estimated global CKD prevalence of 11-13%. Since this is a large number, requirement of a kidney transplant is large, but the number of deceased donors has not risen to match the demand. The gap between potential recipients and organs available could be addressed either by listing fewer patients or by increasing the supply of donor organs. Limiting access is not acceptable since any change in this direction would affect well-established listing indications. The only alternative to this is hemodialysis catheters, and hence, this is poised to aid the market growth during the forecast period 2020-2025.

Challenges – Hemodialysis Catheter Market

  • Long term risks and side effects of hemodialysis
Long term risks of hemodialysis include two to threefold increased risk of death, a five to 10-fold increased risk of serious infection and increased hospitalization, among others. In addition, there are various side effects of hemodialysis catheters, which include low blood pressure (hypotension), muscle cramps, itching, sleeping problems and anemia. This produces complications and serious health problems in some cases. Hence, it is anticipated to hamper the market growth during the forecast period 2020-2025.

Hemodialysis Catheter Industry Outlook
Product launches, mergers and acquisitions, joint ventures and R&D activities are key strategies adopted by players in the Hemodialysis Catheter Market. In 2019, Hemodialysis Catheter Market share is consolidated by the top players present in the market. Hemodialysis Catheter Market top 10 companies are Allmed Medical Corp, Asahi Kasei Medical Co, Ltd, B. Braun Melsungen Ag, Baxter International Inc, Fresenius Se Co. Kgaa, Nikkiso Co Ltd, Nipro Medical Corporation, Nxstage Medical, Inc, Outset Medical, Inc and Toray Medical Co, Ltd among others.

Acquisitions/Product Launches
  • In October 2019, Asahi Kasei Medical acquired ViruSure Forschung und Entwicklung GmbH (ViruSure), an Austrian provider of biosafety testing services. The acquisition wass part of a strategic expansion and reinforcement of Asahi Kasei Medical’s bioprocess business. Consequently, it would also help in expanding the catheter training and business of Asahi.
  • In June 2018, Fresenius Medical Care and Humacyte announced strategic global partnership supported by a $150M equity investment. This aimed at dialysis vascular access option with the potential for significant clinical efficacy and safety improvements, including the potential to minimize catheter contact time to the benefit of patients.
  • In February 2016, Nipro Medical Corporation launched the Cronus™ HP 0.035" OTW PTA Balloon Catheter in the U.S.

1. Hemodialysis Catheter Market Overview
    1.1 Definitions and Scope
2. Hemodialysis Catheter Market - Executive Summary
    2.1 Market Revenue and Key Trends by Company
    2.2 Key trends by Product Type
    2.3 Key trends by Material 
    2.4 Key trends by Geography
3. Hemodialysis Catheter Market – Comparative Analysis
    3.1 Product Benchmarking – Key Companies
    3.2 Financial Analysis – Key Companies
    3.3 Market Value Split by Key Companies
    3.4 Patent Analysis – Key Companies
    3.5 Pricing Analysis
4. Hemodialysis Catheter Market - Startup Companies Scenario (Premium)
    4.1 Key Startup Company Analysis by
        4.1.1 Investment
        4.1.2 Revenue
        4.1.3 Venture Capital and Funding Scenario
5. Hemodialysis Catheter Market – Industry Market Entry Scenario Premium (Premium)
    5.1 Regulatory Framework Overview
    5.2 New Business and Ease of Doing business index
    5.3 Case Studies of Successful Ventures
6. Hemodialysis Catheter Market Forces
    6.1 Market Drivers
    6.2 Market Constraints/Challenges
    6.3 Porters five force model
        6.3.1 Bargaining power of suppliers
        6.3.2 Bargaining powers of customers
        6.3.3 Threat of new entrants
        6.3.4 Rivalry among existing players
        6.3.5 Threat of substitutes 
7. Hemodialysis Catheter Market – Strategic Analysis
    7.1 Value Chain Analysis
    7.2 Opportunities Analysis
    7.3 Market Life Cycle
8. Hemodialysis Catheter Market – By Product Type (Market Size –$Million/$Billion)
    8.1 Cuffed Tunneled Catheter
    8.2 Non-Cuffed Tunneled Catheter
    8.3 Non-Tunneled Catheter
9. Hemodialysis Catheter Market – By Tip Configuration (Market Size –$Million/$Billion)
    9.1 Step-Tip Catheter
    9.2 Split-Tip Catheter
    9.3 Symmetric Catheter
10. Hemodialysis Catheter Market – By Material (Market Size –$Million/$Billion)
    10.1 Silicone
    10.2 Polyurethane
11. Hemodialysis Catheter Market – By End User (Market Size –$Million/$Billion)
    11.1 Hospital
    11.2 Clinics/ Dialysis Center
    11.3 Home Dialysis
12. Hemodialysis Catheter Market – By Geography (Market Size –$Million/$Billion)
    12.1 North America
        12.1.1 U.S.
        12.1.2 Canada
        12.1.3 Mexico
    12.2 Europe
        12.2.1 U.K.
        12.2.2 Germany
        12.2.3 France
        12.2.4 Italy
        12.2.5 Spain
        12.2.6 Rest of Europe
    12.3 Asia-Pacific
        12.3.1 China
        12.3.2 India
        12.3.3 Japan
        12.3.4 South Korea
        12.3.5 Australia & New Zealand
        12.3.6 Rest of Asia-Pacific
    12.4 Rest of the World
        12.4.1 Middle East
        12.4.2 Africa
        12.4.3 South America
13. Hemodialysis Catheter Market - Entropy
14. Hemodialysis Catheter Market – Industry/Segment Competition Landscape (Premium) 
    14.1 Market Share Analysis
        14.1.1 Global Market Share – Key Companies
        14.1.2 Market Share by Region – Key companies
        14.1.3 Market Share by Countries – Key Companies
        14.1.4 Best Practices for Companies
15. Hemodialysis Catheter Market – Key Company List by Country Premium (Premium)
16. Hemodialysis Catheter Market Company Analysis
    16.1 Company 1
    16.2 Company 2
    16.3 Company 3
    16.4 Company 4
    16.5 Company 5
    16.6 Company 6
    16.7 Company 7
    16.8 Company 8
    16.9 Company 9
    16.10 Company 10 and more
"*Financials for private companies would be provided on a best efforts basis”.

LIST OF TABLES

1.Global Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
1.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Global Industry Research
1.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Global Industry Research
1.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Global Industry Research
2.Global Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
2.1 Step-Tip Catheter Market 2019-2024 ($M) - Global Industry Research
2.2 Split-Tip Catheter Market 2019-2024 ($M) - Global Industry Research
2.3 Symmetric Catheter Market 2019-2024 ($M) - Global Industry Research
3.Global Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
3.1 Silicone Market 2019-2024 ($M) - Global Industry Research
3.2 Polyurethane Market 2019-2024 ($M) - Global Industry Research
4.Global Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
4.1 Hospital Market 2019-2024 ($M) - Global Industry Research
4.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Global Industry Research
4.3 Home Dialysis Market 2019-2024 ($M) - Global Industry Research
5.Global Global Hemodialysis Catheter Market, By Product Market 2019-2024 (Volume/Units)
5.1 Cuffed Tunneled Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
5.2 Non-Cuffed Tunneled Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
5.3 Non-Tunneled Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
6.Global Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 (Volume/Units)
6.1 Step-Tip Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
6.2 Split-Tip Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
6.3 Symmetric Catheter Market 2019-2024 (Volume/Units) - Global Industry Research
7.Global Global Hemodialysis Catheter Market, By Material Market 2019-2024 (Volume/Units)
7.1 Silicone Market 2019-2024 (Volume/Units) - Global Industry Research
7.2 Polyurethane Market 2019-2024 (Volume/Units) - Global Industry Research
8.Global Global Hemodialysis Catheter Market, By End User Market 2019-2024 (Volume/Units)
8.1 Hospital Market 2019-2024 (Volume/Units) - Global Industry Research
8.2 Clinics/ Dialysis Center Market 2019-2024 (Volume/Units) - Global Industry Research
8.3 Home Dialysis Market 2019-2024 (Volume/Units) - Global Industry Research
9.North America Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
9.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
9.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
9.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
10.North America Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
10.1 Step-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
10.2 Split-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
10.3 Symmetric Catheter Market 2019-2024 ($M) - Regional Industry Research
11.North America Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
11.1 Silicone Market 2019-2024 ($M) - Regional Industry Research
11.2 Polyurethane Market 2019-2024 ($M) - Regional Industry Research
12.North America Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
12.1 Hospital Market 2019-2024 ($M) - Regional Industry Research
12.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Regional Industry Research
12.3 Home Dialysis Market 2019-2024 ($M) - Regional Industry Research
13.South America Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
13.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
13.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
13.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
14.South America Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
14.1 Step-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
14.2 Split-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
14.3 Symmetric Catheter Market 2019-2024 ($M) - Regional Industry Research
15.South America Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
15.1 Silicone Market 2019-2024 ($M) - Regional Industry Research
15.2 Polyurethane Market 2019-2024 ($M) - Regional Industry Research
16.South America Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
16.1 Hospital Market 2019-2024 ($M) - Regional Industry Research
16.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Regional Industry Research
16.3 Home Dialysis Market 2019-2024 ($M) - Regional Industry Research
17.Europe Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
17.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
17.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
17.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
18.Europe Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
18.1 Step-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
18.2 Split-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
18.3 Symmetric Catheter Market 2019-2024 ($M) - Regional Industry Research
19.Europe Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
19.1 Silicone Market 2019-2024 ($M) - Regional Industry Research
19.2 Polyurethane Market 2019-2024 ($M) - Regional Industry Research
20.Europe Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
20.1 Hospital Market 2019-2024 ($M) - Regional Industry Research
20.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Regional Industry Research
20.3 Home Dialysis Market 2019-2024 ($M) - Regional Industry Research
21.APAC Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
21.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
21.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
21.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
22.APAC Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
22.1 Step-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
22.2 Split-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
22.3 Symmetric Catheter Market 2019-2024 ($M) - Regional Industry Research
23.APAC Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
23.1 Silicone Market 2019-2024 ($M) - Regional Industry Research
23.2 Polyurethane Market 2019-2024 ($M) - Regional Industry Research
24.APAC Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
24.1 Hospital Market 2019-2024 ($M) - Regional Industry Research
24.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Regional Industry Research
24.3 Home Dialysis Market 2019-2024 ($M) - Regional Industry Research
25.MENA Global Hemodialysis Catheter Market, By Product Market 2019-2024 ($M)
25.1 Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
25.2 Non-Cuffed Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
25.3 Non-Tunneled Catheter Market 2019-2024 ($M) - Regional Industry Research
26.MENA Global Hemodialysis Catheter Market, By Tip Configuration Market 2019-2024 ($M)
26.1 Step-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
26.2 Split-Tip Catheter Market 2019-2024 ($M) - Regional Industry Research
26.3 Symmetric Catheter Market 2019-2024 ($M) - Regional Industry Research
27.MENA Global Hemodialysis Catheter Market, By Material Market 2019-2024 ($M)
27.1 Silicone Market 2019-2024 ($M) - Regional Industry Research
27.2 Polyurethane Market 2019-2024 ($M) - Regional Industry Research
28.MENA Global Hemodialysis Catheter Market, By End User Market 2019-2024 ($M)
28.1 Hospital Market 2019-2024 ($M) - Regional Industry Research
28.2 Clinics/ Dialysis Center Market 2019-2024 ($M) - Regional Industry Research
28.3 Home Dialysis Market 2019-2024 ($M) - Regional Industry Research

LIST OF FIGURES

1.US Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
2.Canada Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
3.Mexico Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
4.Brazil Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
5.Argentina Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
6.Peru Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
7.Colombia Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
8.Chile Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
9.Rest of South America Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
10.UK Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
11.Germany Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
12.France Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
13.Italy Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
14.Spain Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
15.Rest of Europe Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
16.China Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
17.India Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
18.Japan Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
19.South Korea Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
20.South Africa Hemodialysis Catheter Market Revenue, 2019-2024 ($M)
21.North America Hemodialysis Catheter By Application
22.South America Hemodialysis Catheter By Application
23.Europe Hemodialysis Catheter By Application
24.APAC Hemodialysis Catheter By Application
25.MENA Hemodialysis Catheter By Application
26.Fresenius Se Co. Kgaa, Sales /Revenue, 2015-2018 ($Mn/$Bn)
27.Nikkiso Co Ltd, Sales /Revenue, 2015-2018 ($Mn/$Bn)
28.B. Braun Melsungen Ag, Sales /Revenue, 2015-2018 ($Mn/$Bn)
29.Nipro Medical Corporation, Sales /Revenue, 2015-2018 ($Mn/$Bn)
30.Toray Medical Co , Ltd, Sales /Revenue, 2015-2018 ($Mn/$Bn)
31.Baxter International Inc, Sales /Revenue, 2015-2018 ($Mn/$Bn)
32.Asahi Kasei Medical Co , Ltd, Sales /Revenue, 2015-2018 ($Mn/$Bn)
33.Nxstage Medical, Inc, Sales /Revenue, 2015-2018 ($Mn/$Bn)
34.Outset Medical, Inc, Sales /Revenue, 2015-2018 ($Mn/$Bn)
35.Allmed Medical Corp, Sales /Revenue, 2015-2018 ($Mn/$Bn)